Publicación:

Experimental infection model for Taenia solium cysticercosis in swine

Resumen

Abstract A novel method for infecting pigs with Taenia solium using an intramuscular innoculum of oncospheres was investigated in a series of five experiments in 18 animals. The model is simple to perform, requires a minimal number of oncospheres, permits multiple infections per animal, and decreases the variation inherent in oral infection models. This intramuscular oncosphere assay (IMOA) may provide a valuable tool to evaluate therapeutic agents or potential vaccines for cysticercosis. Keywords Cysticercosis; Taenia solium; Oncosphere; Experimental infection Abbreviations IMOA, intramuscular oncosphere assay