Publicación:
Whole-Genome Analysis of Bartonella ancashensis, a Novel Pathogen Causing Verruga Peruana, Rural Ancash Region, Peru

dc.contributor.authorMullins, K. E.
dc.contributor.authorHang, J.
dc.contributor.authorClifford, R. J.
dc.contributor.authorOnmus-Leone, F.
dc.contributor.authorYang, Y.
dc.contributor.authorJiang, J.
dc.contributor.authorLeguia, M.
dc.contributor.authorKasper, M. R.
dc.contributor.authorMaguiña Vargas, Ciro
dc.contributor.authorLesho, E. P.
dc.contributor.authorJarman, R. G.
dc.contributor.authorRichards, A.
dc.contributor.authorBlazes, D.
dc.date.accessioned2026-04-28T22:50:48Z
dc.date.issued2017
dc.description.abstractThe genus Bartonella contains >40 species, and an increasing number of these Bartonella species are being implicated in human disease. One such pathogen is Bartonella ancashensis, which was isolated in blood samples from 2 patients living in Caraz, Peru, during a clinical trial of treatment for bartonellosis. Three B. ancashensis strains were analyzed by using whole-genome restriction mapping and high throughput pyrosequencing. Genome-wide comparative analysis of Bartonella species showed that B. ancashensis has features seen in modern and ancient lineages of Bartonella species and is more related to B. bacilliformis. The divergence between B. ancashensis and B. bacilliformis is much greater than what is seen between known Bartonella genetic lineages. In addition, B. ancashensis contains type IV secretion system proteins, which are not present in B. bacilliformis. Whole-genome analysis indicates that B. ancashensis might represent a distinct Bartonella lineage phylogenetically related to B. bacilliformis.en_US
dc.identifier.doihttps://doi.org/10.3201/eid2303.161476
dc.identifier.scopus2-s2.0-85013302188
dc.identifier.urihttps://hdl.handle.net/20.500.12866/19312
dc.language.isoeng
dc.publisherCenters for Disease Control and Prevention
dc.relation.ispartofurn:issn:1080-6059
dc.relation.ispartofseriesEmerging Infectious Diseases
dc.relation.issn1080-6059
dc.rightshttp://purl.org/coar/access_right/c_14cb
dc.subjectbacteremiaen_US
dc.subjectendocarditisen_US
dc.subjectInfectious Diseasesen_US
dc.subjectImmunologyen_US
dc.subjectinfectionen_US
dc.subjectpopulationen_US
dc.subjectdiversityen_US
dc.subjectbacilliformisen_US
dc.subjectnatural-historyen_US
dc.subjectquintanaen_US
dc.subject.ocdehttps://purl.org/pe-repo/ocde/ford#3.03.08
dc.titleWhole-Genome Analysis of Bartonella ancashensis, a Novel Pathogen Causing Verruga Peruana, Rural Ancash Region, Peruen_US
dc.typeinfo:eu-repo/semantics/article
dc.type.localArtículo de revista
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dspace.entity.typePublication

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