Publicación:
Angiotensin Converting Enzyme in Alzheimer's Disease: Increased Activity in Caudate Nucleus and Cortical Areas

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dc.contributor.authorArregui, Alberto
dc.contributor.authorPerry, Elaine K.
dc.contributor.authorRossor, Martin
dc.contributor.authorTomlinson, Bernard E.
dc.date.accessioned2026-05-14T14:28:34Z
dc.date.issued1982
dc.description.abstractAbstract: The activity of the dipeptidyl carboxypeptidase, angiotensin converting enzyme, was assayed in several brain regions of patients dying with Alzheimer's disease and compared to that of appropriately age‐matched controls. Enzyme activity was found to be elevated by 44% and 41% in the medial hippocampus and parahippocampal gyrus, respectively, and by 27% and 29% in the frontal cortex (area 10 of Brodman) and caudate nucleus, respectively, in Alzheimer's disease patients. Converting enzyme activity did not differ from controls in the nucleus accumbens, substantia nigra, temporal cortex, anterior or posterior hippocampus, amygdala, and septal nuclei. Copyright © 1982, Wiley Blackwell. All rights reserveden_US
dc.identifier.doihttps://doi.org/10.1111/j.1471-4159.1982.tb07930.x
dc.identifier.scopus2-s2.0-0020326438
dc.identifier.urihttps://hdl.handle.net/20.500.12866/19692
dc.language.isoeng
dc.publisherJohn Wiley and Sons Inc
dc.relation.ispartofurn:issn:0022-3042
dc.relation.ispartofseriesJournal of Neurochemistry
dc.relation.issn0022-3042
dc.rightshttp://purl.org/coar/access_right/c_14cb
dc.subjectAlzheimer's diseaseen_US
dc.subjectAngiotensin converting enzymeen_US
dc.subjectDementiaen_US
dc.subjectKininase ITen_US
dc.titleAngiotensin Converting Enzyme in Alzheimer's Disease: Increased Activity in Caudate Nucleus and Cortical Areasen_US
dc.typehttps://purl.org/coar/resource_type/c_2df8fbb1
dc.type.localArtículo de revista
dspace.entity.typePublication

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