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Feasibility of noninvasive positive pressure ventilation in the treatment of oxygen-dependent COVID-19 patients in Peru

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dc.contributor.author Cárcamo García, Paloma Mariana
dc.contributor.author Laca-Barrera, M.
dc.contributor.author Cabanillas-Silva, D.
dc.contributor.author Málaga Rodríguez, Germán Javier
dc.contributor.author Mallma-Salazar, P.
dc.contributor.author Moore, David Alexander James
dc.contributor.author Shipley, R.
dc.contributor.author Singer, M.
dc.contributor.author Garcia Funegra, Patricia Jannet
dc.date.accessioned 2021-12-12T20:24:52Z
dc.date.available 2021-12-12T20:24:52Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/20.500.12866/10182
dc.description.abstract Intensive care is expensive, and availability is limited. Low- and middle-income countries in particular have struggled to cope with the large influx of critically ill patients during the COVID-19 pandemic. Noninvasive respiratory support devices delivering continuous positive airways pressure (CPAP) require less resource and staff expertise compared with invasive mechanical ventilators and can be routinely used outside of intensive care units. This study assessed the use of the UCL-Ventura Wayrachi CPAP device in hospitalized patients with COVID-19 in Peru. A secondary analysis of data collected for a feasibility study commissioned by the Peruvian Ministry of Health was conducted. Data were collected from three hospitals, including patient demographics, clinical data, and outcomes. Forty-five patients were enrolled from July 16 to September 1, 2020. Eight patients (18%) were intolerant of the CPAP mask. Of the remainder, 18 (48.7%) improved and were discharged from hospital after 6 days. Eight (21.6%) died while on CPAP and 11 (29.7%) were eventually intubated, of whom two died. In total, 27 (60%) survived to hospital discharge. Participating physicians noted the device was easy to use and provided patient benefit, though voiced concerns about the strain on hospital oxygen supplies. In conclusion, the UCL Ventura Wayrachi CPAP device proved feasible in COVID-19 patients in Peru, and offered a bridging therapy for patients who required a ventilator when none were available en_US
dc.language.iso eng
dc.publisher American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries American Journal of Tropical Medicine and Hygiene
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject adult en_US
dc.subject Adult en_US
dc.subject aged en_US
dc.subject Aged en_US
dc.subject Continuous Positive Airway Pressure en_US
dc.subject COVID-19 en_US
dc.subject Feasibility Studies en_US
dc.subject feasibility study en_US
dc.subject female en_US
dc.subject Female en_US
dc.subject human en_US
dc.subject Humans en_US
dc.subject male en_US
dc.subject Male en_US
dc.subject middle aged en_US
dc.subject Middle Aged en_US
dc.subject noninvasive ventilation en_US
dc.subject Noninvasive Ventilation en_US
dc.subject oxygen en_US
dc.subject Oxygen en_US
dc.subject positive end expiratory pressure ventilation en_US
dc.subject SARS-CoV-2 en_US
dc.subject therapy en_US
dc.subject young adult en_US
dc.subject Young Adult en_US
dc.title Feasibility of noninvasive positive pressure ventilation in the treatment of oxygen-dependent COVID-19 patients in Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.4269/ajtmh.21-0363
dc.relation.issn 1476-1645


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