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Paneth cell identification in the small intestine of guinea pig offsprings (Cavia porcellus)

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dc.contributor.author Vásquez Cachay, María Elith
dc.contributor.author Gomez, Erika Pebe
dc.contributor.author Rodríguez Gutiérrez, José Luis
dc.contributor.author Lira Mejía, Boris
dc.contributor.author Pérez, Néstor Falcón
dc.contributor.author Zanuzzi, Carolina Natalia
dc.contributor.author Barbeito, Claudio
dc.date.accessioned 2022-01-04T20:29:53Z
dc.date.available 2022-01-04T20:29:53Z
dc.date.issued 2014
dc.identifier.uri https://hdl.handle.net/20.500.12866/10367
dc.description.abstract The aim of this study was to determine the presence, number, and morphometrical characteristics of Paneth cells (PC) in the small intestine of guinea pigs during lactation. We used 48 pups from 0 to 15 days old. Samples from small intestine were fixed in 10% buffered formaldehyde (PH 7.4) and processed for histological and morphometrical studies using hematoxylin and eosin (HE), Phloxine tartrazine or Masson's Trichome staining, or immunohistochemistry for lysozyme. PC were morphologically identified at day 2 using Masson's Trichome or Phloxine tartrazine stainings, and at day 4 using HE, whereas using immunohistochemistry they were recognized from birth. Morphometrical differences were found between the intestinal sections at each age studied, and within each section during the first weeks of life. In all developmental stage, the highest number of PC was observed in the duodenum of 13 days old guinea pigs. Our results confirm the presence of PC in the small intestine of guinea pigs from birth. en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartofseries Anatomical Record
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Paneth cells en_US
dc.subject guinea pig en_US
dc.subject lactation en_US
dc.subject immunohisto-chemistry en_US
dc.subject lysozyme en_US
dc.title Paneth cell identification in the small intestine of guinea pig offsprings (Cavia porcellus) en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1002/ar.22890
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.01
dc.relation.issn 1552-4914


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