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dc.contributor.author | Nigo, Masayuki | |
dc.contributor.author | Cevallos, Catalina Salinas | |
dc.contributor.author | Woods, Krystina | |
dc.contributor.author | Flores, Vicente Maco | |
dc.contributor.author | Francis, Gweneth | |
dc.contributor.author | Perlman, David C. | |
dc.contributor.author | Revuelta, Manuel | |
dc.contributor.author | Mildvan, Donna | |
dc.contributor.author | Waldron, Mary | |
dc.contributor.author | Gomez, Tessa | |
dc.contributor.author | Koshy, Sanjana | |
dc.contributor.author | Jodlowski, Tomasz | |
dc.contributor.author | Riley, William | |
dc.contributor.author | Ruhe, Jorg J. | |
dc.date.accessioned | 2022-01-04T20:29:54Z | |
dc.date.available | 2022-01-04T20:29:54Z | |
dc.date.issued | 2013 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/10377 | |
dc.description.abstract | We performed a nested case-control study (ratio of 1:4) on the emergence of tigecycline-resistant multidrug-resistant Klebsiella pneumoniae (TR-MDRKP) isolates among patients who initially presented with a tigecycline-susceptible MDRKP isolate. Out of 260 patients, 24 (9%) had a subsequent clinical culture positive for a TR-MDRKP isolate within the 90-day follow-up period. On logistic regression analyses, receipt of tigecycline (adjusted odds ratio [OR], 5.06; 95% confidence interval [CI], 1.80 to 14.23; P = 0.002) was the only independent predictor of subsequent isolation of a TR strain. | en_US |
dc.language.iso | eng | |
dc.publisher | American Society for Microbiology | |
dc.relation.ispartofseries | Antimicrobial Agents and Chemotherapy | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | human | en_US |
dc.subject | controlled study | en_US |
dc.subject | bacterium culture | en_US |
dc.subject | case control study | en_US |
dc.subject | Aged, 80 and over | en_US |
dc.subject | Time Factors | en_US |
dc.subject | bacterial strain | en_US |
dc.subject | Microbial Sensitivity Tests | en_US |
dc.subject | Anti-Bacterial Agents | en_US |
dc.subject | antibiotic therapy | en_US |
dc.subject | clinical article | en_US |
dc.subject | follow up | en_US |
dc.subject | Follow-Up Studies | en_US |
dc.subject | drug exposure | en_US |
dc.subject | Logistic Models | en_US |
dc.subject | drug treatment failure | en_US |
dc.subject | Drug Resistance, Multiple, Bacterial | en_US |
dc.subject | bacterium isolate | en_US |
dc.subject | aminoglycoside | en_US |
dc.subject | quinolone derivative | en_US |
dc.subject | monotherapy | en_US |
dc.subject | antibiotic resistance | en_US |
dc.subject | cephalosporin | en_US |
dc.subject | Klebsiella pneumoniae | en_US |
dc.subject | tigecycline | en_US |
dc.subject | vancomycin | en_US |
dc.subject | clindamycin | en_US |
dc.subject | urinary tract infection | en_US |
dc.subject | molecular typing | en_US |
dc.subject | aztreonam | en_US |
dc.subject | carbapenem | en_US |
dc.subject | Charlson Comorbidity Index | en_US |
dc.subject | Klebsiella Infections | en_US |
dc.subject | linezolid | en_US |
dc.subject | metronidazole | en_US |
dc.subject | Minocycline | en_US |
dc.subject | multidrug resistant Klebsiella pneumoniae | en_US |
dc.subject | polymyxin | en_US |
dc.title | Nested case-control study of the emergence of tigecycline resistance in multidrug-resistant Klebsiella pneumoniae | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1128/AAC.00827-13 | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.02.21 | |
dc.relation.issn | 1098-6596 |
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