Universidad Peruana Cayetano Heredia

A prospective cohort study characterising the role of anogenital warts in HIV acquisition among men who have sex with men: A study protocol

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dc.contributor.author Brown, Brandon
dc.contributor.author Davtyan, Mariam
dc.contributor.author León Sandoval, Segundo Ramos
dc.contributor.author Sanchez, Hugo
dc.contributor.author Calvo, Gino
dc.contributor.author Klausner, Jeffrey D.
dc.contributor.author Galea, Jerome
dc.date.accessioned 2022-01-04T20:29:55Z
dc.date.available 2022-01-04T20:29:55Z
dc.date.issued 2014
dc.identifier.uri https://hdl.handle.net/20.500.12866/10402
dc.description.abstract Introduction The HIV epidemic in Latin America is concentrated among men who have sex with men (MSM) and transgender women (TGW) with transmission predominately occurring during unprotected anal intercourse. This mode of transmission is also responsible for other sexually transmitted infections (STIs) such as herpes simplex, chlamydia and gonorrhoea, human papillomavirus (HPV)/genital warts and syphilis. Studies assessing the prevalence of HIV and HPV among MSM have not addressed the role of genital warts and HPV-related diseases in the acquisition of HIV infection. Community-based testing programmes are a potentially important way to remove barriers including stigma for individuals to learn about their STI status. Methods: and analysis The prospective cohort study will recruit 600 MSM/TGW at a community centre in Lima, Peru, named Epicentro. Half of the participants will have a history of or have current anogenital warts (AGW), and the other half will have no history of AGW. We will measure the prevalence and acquisition of STIs including syphilis, HPV, chlamydia and gonorrhoea and the HIV-incidence in the two groups. To the best of our knowledge, it will be the first study that specifically examines the impact of genital warts on incident HIV infection. This study will help to understand the relationship between AGW and HIV infection among MSM/TGW in Peru. Furthermore, it may facilitate the development of preventive intervention strategies to reduce the prevalence of AGW and prevent incident HIV infection. HPV-related manifestations may be a good proxy for HIV risk. Ethics and dissemination This study was approved by institutional review boards at the University of California, Los Angeles (UCLA) in the USA and Impacta in Peru. Study findings will be shared with the Peruvian Ministry of Health as well as other international and national public health organisations. Study results will be translated into Spanish for participants. en_US
dc.language.iso eng
dc.publisher BMJ Publishing Group
dc.relation.ispartofseries BMJ Open
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Health survey en_US
dc.subject human en_US
dc.subject major clinical study en_US
dc.subject Peru en_US
dc.subject transmission en_US
dc.subject complication en_US
dc.subject disease association en_US
dc.subject HIV Infections en_US
dc.subject Human immunodeficiency virus infection en_US
dc.subject Transgendered Persons en_US
dc.subject cohort analysis en_US
dc.subject prospective study en_US
dc.subject physical examination en_US
dc.subject Cohort Studies en_US
dc.subject follow up en_US
dc.subject infection risk en_US
dc.subject syphilis en_US
dc.subject infection prevention en_US
dc.subject men who have sex with men en_US
dc.subject health center en_US
dc.subject anus disease en_US
dc.subject Anus Diseases en_US
dc.subject chlamydiasis en_US
dc.subject clinical trial (topic) en_US
dc.subject condyloma acuminatum en_US
dc.subject Condylomata Acuminata en_US
dc.subject counseling en_US
dc.subject gonorrhea en_US
dc.subject HIV test en_US
dc.subject medical history en_US
dc.subject verruca vulgaris en_US
dc.title A prospective cohort study characterising the role of anogenital warts in HIV acquisition among men who have sex with men: A study protocol en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1136/bmjopen-2014-005687
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08
dc.relation.issn 2044-6055


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