Universidad Peruana Cayetano Heredia

Sodium chloride 0 9% versus lactated ringer in the management of severely dehydrated patients with choleriform diarrhoea

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dc.contributor.author Cieza Zevallos, Javier Antonio
dc.contributor.author Hinostroza, Juana
dc.contributor.author Huapaya, Julio Arturo
dc.contributor.author León Rabanal, Cristian Paul
dc.date.accessioned 2022-01-04T20:31:43Z
dc.date.available 2022-01-04T20:31:43Z
dc.date.issued 2013
dc.identifier.uri https://hdl.handle.net/20.500.12866/10562
dc.description.abstract Introduction: Although experience within Peru suggests clinical and physiological benefits of treating dehydration caused by diarrhoea with Lactated Ringer’s solution (LR) over sodium chloride 0.9%, (NaCl) there is little documented scientific evidence supporting this view. It is important to clarify this issue and determine the best solution for use during epidemics. Methodology: Forty patients suffering from dehydration due to choleriform diarrhoea were enrolled in the study. Twenty patients were treated using NaCl (Group A) and the other twenty with LR (Group B). After diuresis recovery was achieved, the patients were continued on a course of oral rehydration salts. Serum electrolytes, arterial pH, HCO3-, and pCO2 were measured at three stages: at admission, after diuresis recovery, and after 12 hours. Results: Acidosis was corrected more quickly with LR that NaCl. The hyperosmolality and hypernatremic states were corrected with both solutions. Conclusion: LR use resulted in a better clinical response than NaCl, illustrated by more rapid physiological correction, showing that mixed metabolic acidosis was corrected more quickly and more appropriately with this treatment. en_US
dc.language.iso eng
dc.publisher Journal of Infection in Developing Countries
dc.relation.ispartofseries Journal of Infection in Developing Countries
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Cholera en_US
dc.subject diarrhoea en_US
dc.subject isotonic solutions en_US
dc.subject Lactated Ringer’s solution en_US
dc.subject rehydration en_US
dc.subject sodium chloride 0 9% en_US
dc.title Sodium chloride 0 9% versus lactated ringer in the management of severely dehydrated patients with choleriform diarrhoea en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.3855/jidc.2531
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08
dc.relation.issn 1972-2680


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