Universidad Peruana Cayetano Heredia
Diagnostic accuracy among 4 point-of-care tests for the screening of HIV infection
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| dc.contributor.author | Flores, Karina | |
| dc.contributor.author | León Sandoval, Segundo Ramos | |
| dc.date.accessioned | 2022-01-04T20:31:44Z | |
| dc.date.available | 2022-01-04T20:31:44Z | |
| dc.date.issued | 2013 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12866/10581 | |
| dc.description.abstract | The aim of this study was to validate and compare 4 point-of-care (POC) devices for the detection of antibodies to human immunodeficiency virus 1 (HIV-1) and/or HIV-2 in cryopreserved serum specimens. We analyzed 99 specimens that had tested positive for antibodies to HIV-1/HIV-2 by Western blot and 101 samples with negative test results. All the samples were analyzed by each of the 4 rapid tests. The POC devices assessed in this study use lateral flow immunochemistry technology and provided results within 15 to 20 minutes. We obtained an average sensitivity of 97.57%, specificity of 98.77%, positive predictive value of 98.52%, and negative predictive value of 97.82%. The among-test correlation was 97.57%, and the kappa index was 0.96. Assessment of the performance of new rapid HIV tests must be regularly practiced where regular enzyme immunoassay (EIA) tests are not widely available. All 4 rapid HIV tests assessed in this study performed with acceptable accuracy. | en_US |
| dc.language.iso | eng | |
| dc.publisher | Oxford University Press | |
| dc.relation.ispartofseries | Laboratory Medicine | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
| dc.subject | HIV rapid test | en_US |
| dc.subject | POC | en_US |
| dc.subject | sensitivity and specificity | en_US |
| dc.subject | Peru | en_US |
| dc.title | Diagnostic accuracy among 4 point-of-care tests for the screening of HIV infection | en_US |
| dc.type | info:eu-repo/semantics/article | |
| dc.identifier.doi | https://doi.org/10.1309/LMUY1PHAC0S0DMJR | |
| dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#2.06.02 | |
| dc.relation.issn | 1943-7730 |
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