Universidad Peruana Cayetano Heredia

Microalbuminuria in healthy adolescents: A comparative study at high altitude and at sea level

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dc.contributor.author Hurtado, Abdias
dc.contributor.author Cancino, Raquel
dc.contributor.author Figueroa, Joel
dc.contributor.author Padilla, Euclides
dc.contributor.author Morales, Christian
dc.contributor.author Ortiz, Irma
dc.contributor.author Sharma, Shailendra
dc.contributor.author Johnson, Richard J.
dc.contributor.author Pando, Jackeline
dc.date.accessioned 2022-01-04T20:31:46Z
dc.date.available 2022-01-04T20:31:46Z
dc.date.issued 2014
dc.identifier.uri https://hdl.handle.net/20.500.12866/10624
dc.description.abstract Background : High altitude is associated with hypobaric hypoxia and increased risk for microalbuminuria in adults. We hypothesized that healthy adolescents at higher altitude might have an increased frequency of microalbuminuria in comparison with a group of adolescents living at sea level. Methods: : We evaluated the presence of microalbuminuria in adolescents at sea level (n=68, altitude 130 meters) and at high altitude (n=114, altitude 3200 meters) living in Peru. Each subject was evaluated for body mass index, Blood Pressure, microalbuminuria, proteinuria, hematuria and leukocyturia in a first morning urine sample. Subjects with a positive test for microalbuminuria underwent repeat testing one or two weeks after the initial screening. Results : Subjects at sea level and high altitude had similar age, weight, height and blood pressure (p=NS). Microalbuminuria without any other urinary abnormality, was higher in the first screening among adolescents residing at high altitude compared to those living at sea level (42 vs15, p: 0.0215). In the second screening the results were similar in both groups (31 vs 11, p: 0.0879). Conclusion: : Persistent microalbuminuria was observed in more than one-quarter of adolescents living at high altitude. This study suggests that subtle renal injury may occur early in subjects living at high altitude. en_US
dc.language.iso eng
dc.publisher Bentham Open
dc.relation.ispartofseries Open Urology and Nephrology Journal
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Adolescents en_US
dc.subject high altitude en_US
dc.subject microalbuminuria en_US
dc.title Microalbuminuria in healthy adolescents: A comparative study at high altitude and at sea level en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.2174/1874303X01407010082
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.20
dc.relation.issn 1874-303X


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