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dc.contributor.author | Feldman, Kristyn E. | |
dc.contributor.author | Loriaux, Paul M. | |
dc.contributor.author | Saito, Mayuko | |
dc.contributor.author | Tuero Ochoa, Iskra | |
dc.contributor.author | Villaverde, Homarh | |
dc.contributor.author | Siva, Tenaya | |
dc.contributor.author | Gotuzzo Herencia, José Eduardo | |
dc.contributor.author | Gilman, Robert Hugh | |
dc.contributor.author | Hoffmann, Alexander | |
dc.contributor.author | Vinetz, Joseph Michael | |
dc.date.accessioned | 2022-01-04T20:31:47Z | |
dc.date.available | 2022-01-04T20:31:47Z | |
dc.date.issued | 2013 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/10658 | |
dc.description.abstract | Brucellosis, a zoonotic infection caused by one of the Gram-negative intracellular bacteria of the Brucella genus, is an ongoing public health problem in Perú. While most patients who receive standard antibiotic treatment recover, 5–40% suffer a brucellosis relapse. In this study, we examined the ex vivo immune cytokine profiles of recovered patients with a history of acute and relapsing brucellosis. | en_US |
dc.language.iso | eng | |
dc.publisher | Public Library of Science | |
dc.relation.ispartofseries | PLoS Neglected Tropical Diseases | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | gene expression | en_US |
dc.subject | Humans | en_US |
dc.subject | Peru | en_US |
dc.subject | controlled study | en_US |
dc.subject | innate immunity | en_US |
dc.subject | interleukin 4 | en_US |
dc.subject | interleukin 5 | en_US |
dc.subject | human cell | en_US |
dc.subject | real time polymerase chain reaction | en_US |
dc.subject | Real-Time Polymerase Chain Reaction | en_US |
dc.subject | cytokine | en_US |
dc.subject | Cytokines | en_US |
dc.subject | article | en_US |
dc.subject | clinical article | en_US |
dc.subject | gamma interferon | en_US |
dc.subject | interleukin 10 | en_US |
dc.subject | tumor necrosis factor alpha | en_US |
dc.subject | relapse | en_US |
dc.subject | Cells, Cultured | en_US |
dc.subject | Leukocytes, Mononuclear | en_US |
dc.subject | peripheral blood mononuclear cell | en_US |
dc.subject | Recurrence | en_US |
dc.subject | recurrence risk | en_US |
dc.subject | Brucella melitensis | en_US |
dc.subject | brucellosis | en_US |
dc.subject | Brucellosis | en_US |
dc.subject | Risk Assessment | en_US |
dc.subject | interleukin 6 | en_US |
dc.subject | Gene Expression Profiling | en_US |
dc.subject | interleukin 1beta | en_US |
dc.subject | interleukin 8 | en_US |
dc.subject | Culture Media | en_US |
dc.subject | Immunity, Innate | en_US |
dc.subject | interleukin 2 | en_US |
dc.subject | granulocyte macrophage colony stimulating factor | en_US |
dc.subject | immunoassay | en_US |
dc.subject | Immunoassay | en_US |
dc.subject | protein secretion | en_US |
dc.subject | toll like receptor agonist | en_US |
dc.title | Ex Vivo Innate Immune Cytokine Signature of Enhanced Risk of Relapsing Brucellosis | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1371/journal.pntd.0002424 | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.03.06 | |
dc.relation.issn | 1935-2735 |
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