Effects of Ascent to High Altitude on Human Antimycobacterial Immunity

Gilman, Robert Hugh; Aldridge, Robert W.; Herrera, Beatriz; Leybell, Inna; Friedland, Jon S.; Eisen, Sarah; Valencia, Teresa; Wiles, Siouxsie; Siedner, Mark J.; Evans, Carlton Anthony William; Pealing, Louise; Necochea, Alejandro

dc.contributor.author	Eisen, Sarah
dc.contributor.author	Pealing, Louise
dc.contributor.author	Aldridge, Robert W.
dc.contributor.author	Siedner, Mark J.
dc.contributor.author	Necochea, Alejandro
dc.contributor.author	Leybell, Inna
dc.contributor.author	Valencia, Teresa
dc.contributor.author	Herrera, Beatriz
dc.contributor.author	Wiles, Siouxsie
dc.contributor.author	Friedland, Jon S.
dc.contributor.author	Gilman, Robert Hugh
dc.contributor.author	Evans, Carlton Anthony William
dc.date.accessioned	2022-01-04T20:31:49Z
dc.date.available	2022-01-04T20:31:49Z
dc.date.issued	2013
dc.identifier.uri	https://hdl.handle.net/20.500.12866/10707
dc.description.abstract	Tuberculosis infection, disease and mortality are all less common at high than low altitude and ascent to high altitude was historically recommended for treatment. The immunological and mycobacterial mechanisms underlying the association between altitude and tuberculosis are unclear. We studied the effects of altitude on mycobacteria and antimycobacterial immunity.	en_US
dc.language.iso	eng
dc.publisher	Public Library of Science
dc.relation.ispartofseries	PLoS ONE
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Humans	en_US
dc.subject	controlled study	en_US
dc.subject	bacterial growth	en_US
dc.subject	bacterium culture	en_US
dc.subject	Mycobacterium	en_US
dc.subject	blood	en_US
dc.subject	altitude	en_US
dc.subject	Biological Assay	en_US
dc.subject	culture medium	en_US
dc.subject	Blood	en_US
dc.subject	plasma	en_US
dc.subject	antimycobacterial immunity	en_US
dc.subject	bacterial immunity	en_US
dc.subject	bacterium colony	en_US
dc.subject	Blood Bactericidal Activity	en_US
dc.subject	Cell Engineering	en_US
dc.subject	Colony Count, Microbial	en_US
dc.subject	Culture Media	en_US
dc.subject	Immunity, Innate	en_US
dc.subject	luminescence	en_US
dc.subject	Luminescence	en_US
dc.subject	Microbial Viability	en_US
dc.subject	Mycobacterium bovis	en_US
dc.title	Effects of Ascent to High Altitude on Human Antimycobacterial Immunity	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1371/journal.pone.0074220
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#1.06.01
dc.relation.issn	1932-6203