Changes in tuberculin skin test positivity over 20 years in periurban shantytowns in Lima, Peru

Gilman, Robert Hugh; Martinez, Leonardo; Haveman, Nathan; Collazo, Gisela; Saito, Mayuko; Carnero, Andrés M.; Oberhelman, Richard; Arman, Alyssa; Lundgren, Ashley; Evans, Carlton Anthony William; Cabrera, Lilia; Callacondo, David; Pelly, Tom F.

dc.contributor.author	Martinez, Leonardo
dc.contributor.author	Arman, Alyssa
dc.contributor.author	Haveman, Nathan
dc.contributor.author	Lundgren, Ashley
dc.contributor.author	Cabrera, Lilia
dc.contributor.author	Evans, Carlton Anthony William
dc.contributor.author	Pelly, Tom F.
dc.contributor.author	Saito, Mayuko
dc.contributor.author	Callacondo, David
dc.contributor.author	Oberhelman, Richard
dc.contributor.author	Collazo, Gisela
dc.contributor.author	Carnero, Andrés M.
dc.contributor.author	Gilman, Robert Hugh
dc.date.accessioned	2022-01-04T20:33:20Z
dc.date.available	2022-01-04T20:33:20Z
dc.date.issued	2013
dc.identifier.uri	https://hdl.handle.net/20.500.12866/10750
dc.description.abstract	A cross-sectional, community-based study was performed in 2012 with 428 residents of periurban shantytowns in Lima, Peru to study risk factors for and changes in latent tuberculosis infection in age-stratified groups compared with our data from the same region in 1990 (N = 219) and 2005 (N = 103). Tuberculin skin test positivity in these communities was highly prevalent at 52% overall, increased with age (P < 0.01) and was similar to 2005 (53%) and 1990 (48%). From 1990 to 2012, the prevalence of tuberculin positivity decreased in 5–14 and 15–24 year old groups (to 17% and 34%, respectively, both P < 0.05). However, this may be explained by cessation of Bacille Calmette-Guérin revaccination during this period, because Bacille Calmette-Guérin revaccination doubled tuberculin positivity. Over the same 22-year period, tuberculin positivity in the ≥ 25 year old group remained high (71%, P = 0.3), suggesting that prevalent latent tuberculosis infection persists in the adult population despite improving medical care and socioeconomic development in this region.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Cross-Sectional Studies	en_US
dc.subject	major clinical study	en_US
dc.subject	Peru	en_US
dc.subject	prevalence	en_US
dc.subject	Young Adult	en_US
dc.subject	risk factor	en_US
dc.subject	urban area	en_US
dc.subject	Socioeconomic Factors	en_US
dc.subject	infection control	en_US
dc.subject	latent tuberculosis	en_US
dc.subject	tuberculin test	en_US
dc.subject	resident	en_US
dc.subject	BCG vaccination	en_US
dc.subject	groups by age	en_US
dc.subject	Latent Tuberculosis	en_US
dc.subject	revaccination	en_US
dc.title	Changes in tuberculin skin test positivity over 20 years in periurban shantytowns in Lima, Peru	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.13-0005
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645