Universidad Peruana Cayetano Heredia

Changes in tuberculin skin test positivity over 20 years in periurban shantytowns in Lima, Peru

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dc.contributor.author Martinez, Leonardo
dc.contributor.author Arman, Alyssa
dc.contributor.author Haveman, Nathan
dc.contributor.author Lundgren, Ashley
dc.contributor.author Cabrera, Lilia
dc.contributor.author Evans, Carlton Anthony William
dc.contributor.author Pelly, Tom F.
dc.contributor.author Saito, Mayuko
dc.contributor.author Callacondo, David
dc.contributor.author Oberhelman, Richard
dc.contributor.author Collazo, Gisela
dc.contributor.author Carnero, Andrés M.
dc.contributor.author Gilman, Robert Hugh
dc.date.accessioned 2022-01-04T20:33:20Z
dc.date.available 2022-01-04T20:33:20Z
dc.date.issued 2013
dc.identifier.uri https://hdl.handle.net/20.500.12866/10750
dc.description.abstract A cross-sectional, community-based study was performed in 2012 with 428 residents of periurban shantytowns in Lima, Peru to study risk factors for and changes in latent tuberculosis infection in age-stratified groups compared with our data from the same region in 1990 (N = 219) and 2005 (N = 103). Tuberculin skin test positivity in these communities was highly prevalent at 52% overall, increased with age (P < 0.01) and was similar to 2005 (53%) and 1990 (48%). From 1990 to 2012, the prevalence of tuberculin positivity decreased in 5–14 and 15–24 year old groups (to 17% and 34%, respectively, both P < 0.05). However, this may be explained by cessation of Bacille Calmette-Guérin revaccination during this period, because Bacille Calmette-Guérin revaccination doubled tuberculin positivity. Over the same 22-year period, tuberculin positivity in the ≥ 25 year old group remained high (71%, P = 0.3), suggesting that prevalent latent tuberculosis infection persists in the adult population despite improving medical care and socioeconomic development in this region. en_US
dc.language.iso eng
dc.publisher American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries American Journal of Tropical Medicine and Hygiene
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Cross-Sectional Studies en_US
dc.subject major clinical study en_US
dc.subject Peru en_US
dc.subject prevalence en_US
dc.subject Young Adult en_US
dc.subject risk factor en_US
dc.subject urban area en_US
dc.subject Socioeconomic Factors en_US
dc.subject infection control en_US
dc.subject latent tuberculosis en_US
dc.subject tuberculin test en_US
dc.subject resident en_US
dc.subject BCG vaccination en_US
dc.subject groups by age en_US
dc.subject Latent Tuberculosis en_US
dc.subject revaccination en_US
dc.title Changes in tuberculin skin test positivity over 20 years in periurban shantytowns in Lima, Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.4269/ajtmh.13-0005
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn 1476-1645


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