Case report: Histopathological features of tungiasis in Peru

Maco, Vicente P.; Gotuzzo Herencia, José Eduardo; Tantalean, Manuel E.; Maco, Vicente

dc.contributor.author	Maco, Vicente
dc.contributor.author	Maco, Vicente P.
dc.contributor.author	Tantalean, Manuel E.
dc.contributor.author	Gotuzzo Herencia, José Eduardo
dc.date.accessioned	2022-01-04T20:33:21Z
dc.date.available	2022-01-04T20:33:21Z
dc.date.issued	2013
dc.identifier.uri	https://hdl.handle.net/20.500.12866/10769
dc.description.abstract	Tungiasis is an ectoparasitic skin disease caused byTunga penetransandTunga trimamillata. There is a lackof histopathological studies that evaluate the recognition of this flea in tissues. We describe theex vivodermoscopic and thehistopathological patterns of six cases and relate the findings to the developmental stage of the parasite as defined by theFortaleza classification: two were classified as Fortaleza 3b, 3 as 4a, and 1 as 4b. Two dermoscopic patterns were observed:a brown pigmented ring and a radial crown with a central pore. The most common histopathological findings were aneosinophilic cuticle, eggs in different stages of development, tracheal rings (parasite), and basal hyperplasia (host). Theeosinophilic cuticle, eggs in different stages of evolution, and tracheal rings can help to establish the diagnosis when otherparts of the parasite are lacking. The Fortaleza staging may represent a tool for pathology reporting purposes.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Animals	en_US
dc.subject	human	en_US
dc.subject	Peru	en_US
dc.subject	pathology	en_US
dc.subject	case report	en_US
dc.subject	Prospective Studies	en_US
dc.subject	multicenter study	en_US
dc.subject	histopathology	en_US
dc.subject	skin biopsy	en_US
dc.subject	clinical growth, development and aging	en_US
dc.subject	methodology	en_US
dc.subject	ex vivo study	en_US
dc.subject	bacterium colony	en_US
dc.subject	acanthosis	en_US
dc.subject	chitin	en_US
dc.subject	Dermoscopy	en_US
dc.subject	epiluminescence microscopy	en_US
dc.subject	hyperkeratosis	en_US
dc.subject	papillomatosis	en_US
dc.subject	parakeratosis	en_US
dc.subject	parasite development	en_US
dc.subject	Siphonaptera (fleas)	en_US
dc.subject	staging	en_US
dc.subject	subcutaneous tissue	en_US
dc.subject	Tunga penetrans	en_US
dc.subject	Tunga trimamillata	en_US
dc.subject	tungiasis	en_US
dc.title	Case report: Histopathological features of tungiasis in Peru	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.12-0645
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645