Universidad Peruana Cayetano Heredia

Launching a salt substitute to reduce blood pressure at the population level: A cluster randomized stepped wedge trial in Peru

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dc.contributor.author Bernabé Ortiz, Antonio
dc.contributor.author Diez-Canseco Montero, Francisco
dc.contributor.author Gilman, Robert Hugh
dc.contributor.author Cárdenas García-Santillán, María Kathia
dc.contributor.author Sacksteder, Katherine A.
dc.contributor.author Miranda, J. Jaime
dc.date.accessioned 2022-01-04T20:33:21Z
dc.date.available 2022-01-04T20:33:21Z
dc.date.issued 2014
dc.identifier.uri https://hdl.handle.net/20.500.12866/10780
dc.description.abstract Background: Controlling hypertension rates and maintaining normal blood pressure, particularly in resource-constrained settings, represent ongoing challenges of effective and affordable implementation in health care. One of the strategies being largely advocated to improve high blood pressure calls for salt reduction strategies. This study aims to estimate the impact of a population-level intervention based on sodium reduction and potassium increase – in practice, introducing a low-sodium, high-potassium salt substitute – on adult blood pressure levels. Methods/Design: The proposed implementation research study includes two components: Phase 1, an exploratory component, and Phase 2, an intervention component. The exploratory component involves a triangle taste test and a formative research study designed to gain an understanding of the best implementation methods. Phase 2 involves a pragmatic stepped wedge trial design where the intervention will be progressively implemented in several clusters starting the intervention randomly at different times. In addition, we will evaluate the implementation strategy using a cost-effectiveness analysis. Discussion: This is the first project in a Latin-American setting to implement a salt substitution intervention at the population level to tackle high blood pressure. Data generated and lessons learnt from this study will provide a strong platform to address potential interventions applicable to other similar low- and middle-income settings. en_US
dc.language.iso eng
dc.publisher BioMed Central
dc.relation.ispartofseries Trials
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Humans en_US
dc.subject Peru en_US
dc.subject Young Adult en_US
dc.subject Treatment Outcome en_US
dc.subject Time Factors en_US
dc.subject Clinical Protocols en_US
dc.subject Recommended Dietary Allowances en_US
dc.subject Taste en_US
dc.subject Blood Pressure en_US
dc.subject Diet Sodium-Restricted en_US
dc.subject Hypertension en_US
dc.subject Potassium en_US
dc.subject Sodium Chloride en_US
dc.title Launching a salt substitute to reduce blood pressure at the population level: A cluster randomized stepped wedge trial in Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1186/1745-6215-15-93
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.06
dc.relation.issn 1745-6215


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