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Tobacco use and dementia: Evidence from the 1066 dementia population-based surveys in Latin America, China and India

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dc.contributor.author Ferri, C.P.
dc.contributor.author West, R.
dc.contributor.author Moriyama, T.S.
dc.contributor.author Acosta, D.
dc.contributor.author Guerra Arteaga, Mariella
dc.contributor.author Huang, Y.
dc.contributor.author Jacob, K.S.
dc.contributor.author Ribeiro, W.
dc.contributor.author Llibre De Rodriguez, J.J.
dc.contributor.author Salas, A.
dc.contributor.author Sosa, A.L.
dc.contributor.author Williams, J.
dc.contributor.author Acosta, I.
dc.contributor.author Liu, Z.
dc.contributor.author Hernandez, M.A.G.
dc.contributor.author Prince, M.J.
dc.date.accessioned 2022-01-18T19:26:44Z
dc.date.available 2022-01-18T19:26:44Z
dc.date.issued 2011
dc.identifier.uri https://hdl.handle.net/20.500.12866/10818
dc.description.abstract Objectives: To assess the association between tobacco consumption and dementia using the same methodology in seven developing countries, testing the specific hypotheses that higher exposure to tobacco is associated with a higher prevalence of dementia, that the association is limited to smoked tobacco and is stronger for vascular dementia compared to Alzheimer's disease. Methods: Cross-sectional surveys conducted on individuals aged 65+. A total of 15 022 residents in specified catchment areas were assessed face-to-face using a standardised protocol, which included dementia diagnosis and detailed information on past and current tobacco consumption, and on important potential confounders of this association. Results: A high proportion of participants were never smokers (52% in Dominican Republic to 83% in Peru), most of those who ever used tobacco in China and India were still smoking at age 65 and above (80% and 84%, respectively). There was a positive association between history of tobacco smoke exposure (pack years up to age 50) and dementia (pooled PR = 1.003; 95%CI 1.001-1.005), Alzheimer's disease (pooled PR = 1.007; 95% CI, 1.003-1.011) and Vascular Dementia (pooled PR = 1.003; 95% CI = 1.001-1.005). These associations were attenuated but remained significant if exposure after the age of 50 was included. In India there was no association between smokeless tobacco and dementia. Conclusions: Dementia in developing countries appears to be positively associated with history of tobacco smoking but not smokeless tobacco use. Selective quitting in later life may bias estimation of associations. en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartofseries International Journal of Geriatric Psychiatry
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Aged 80 And Over en_US
dc.subject Humans en_US
dc.subject Peru en_US
dc.subject Controlled Study en_US
dc.subject Major Clinical Study en_US
dc.subject Disease Association en_US
dc.subject Prevalence en_US
dc.subject Latin America en_US
dc.subject South And Central America en_US
dc.subject Health Survey en_US
dc.subject China en_US
dc.subject Environmental Exposure en_US
dc.subject Developing Country en_US
dc.subject Mexico en_US
dc.subject Life Style en_US
dc.subject Dominican Republic en_US
dc.subject Evidence Based Medicine en_US
dc.subject Medical History en_US
dc.subject Venezuela en_US
dc.subject Cuba en_US
dc.subject Dementia en_US
dc.subject India en_US
dc.subject Developing Countries en_US
dc.subject Alzheimer Disease en_US
dc.subject Alzheimer's Disease en_US
dc.subject Multiinfarct Dementia en_US
dc.subject Smokeless Tobacco en_US
dc.subject Tobacco Smoke en_US
dc.subject Tobacco Use en_US
dc.subject Vascular Dementia en_US
dc.title Tobacco use and dementia: Evidence from the 1066 dementia population-based surveys in Latin America, China and India en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1002/gps.2661
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.24
dc.relation.issn 1099-1166


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