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A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings

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dc.contributor.author Hartinger Peña, Stella Maria
dc.contributor.author Lanata, C.F.
dc.contributor.author Hattendorf, J.
dc.contributor.author Gil, A.I.
dc.contributor.author Verástegui Huasasquiche, Héctor Alfredo
dc.contributor.author Ochoa Woodell, Theresa Jean
dc.contributor.author Mäusezahl, D.
dc.date.accessioned 2022-01-18T19:26:45Z
dc.date.available 2022-01-18T19:26:45Z
dc.date.issued 2011
dc.identifier.uri https://hdl.handle.net/20.500.12866/10845
dc.description.abstract Introduction: Pneumonia and diarrhoea are leading causes of death in children. There is a need to develop effective interventions. Objective: We present the design and baseline findings of a community-randomised controlled trial in rural Peru to evaluate the health impact of an Integrated Home-based Intervention Package in children aged 6 to 35. months. Methods: We randomised 51 communities. The intervention was developed through a community-participatory approach prior to the trial. They comprised the construction of improved stoves and kitchen sinks, the promotion of hand washing, and solar drinking water disinfection (SODIS). To reduce the potential impact of non-blinding bias, a psychomotor stimulation intervention was implemented in the control arm. The baseline survey included anthropometric and socio-economic characteristics. In a sub-sample we determined the level of faecal contamination of drinking water, hands and kitchen utensils and the prevalence of diarrhoegenic Escherichia coli in stool specimen. Results: We enrolled 534 children. At baseline all households used open fires and 77% had access to piped water supplies. E. coli was found in drinking water in 68% and 64% of the intervention and control households. Diarrhoegenic E. coli strains were isolated from 45/139 stool samples. The proportion of stunted children was 54%. Conclusions: Randomization resulted in comparable study arms. Recently, several critical reviews raised major concerns on the reliability of open health intervention trials, because of uncertain sustainability and non-blinding bias. In this regard, the presented trial featuring objective outcome measures, a simultaneous intervention in the control communities and a 12-month follow up period will provide valuable evidence. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Contemporary Clinical Trials
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Child, Preschool en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Peru en_US
dc.subject article en_US
dc.subject controlled study en_US
dc.subject major clinical study en_US
dc.subject Infant en_US
dc.subject Retrospective Studies en_US
dc.subject randomized controlled trial (topic) en_US
dc.subject Follow-Up Studies en_US
dc.subject Environmental Exposure en_US
dc.subject infant en_US
dc.subject Rural Population en_US
dc.subject socioeconomics en_US
dc.subject feces en_US
dc.subject Incidence en_US
dc.subject drinking water en_US
dc.subject household en_US
dc.subject water contamination en_US
dc.subject treatment outcome en_US
dc.subject home care en_US
dc.subject bacterium isolation en_US
dc.subject diarrheagenic Escherichia coli en_US
dc.subject bacterial strain en_US
dc.subject feces microflora en_US
dc.subject hand washing en_US
dc.subject Disinfection en_US
dc.subject anthropometric parameters en_US
dc.subject acute diarrhea en_US
dc.subject Acute lower respiratory infections en_US
dc.subject ambient air en_US
dc.subject bacterium contamination en_US
dc.subject Child health en_US
dc.subject Diarrhoea en_US
dc.subject Environmental Illness en_US
dc.subject environmental sanitation en_US
dc.subject Hand-washing en_US
dc.subject health promotion en_US
dc.subject home based intervention package en_US
dc.subject Household Articles en_US
dc.subject Hygiene en_US
dc.subject kitchen en_US
dc.subject lower respiratory tract infection en_US
dc.subject psychomotor development en_US
dc.subject solar drinking water disinfection en_US
dc.subject Sunlight en_US
dc.subject water management en_US
dc.subject Water Supply en_US
dc.title A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.cct.2011.06.006
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.00
dc.relation.issn 1551-7144

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