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Co-occurrence of anxiety and depression amongst older adults in low-and middle-income countries: Findings from the 10/66 study

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dc.contributor.author Prina, A.M.
dc.contributor.author Ferri, C.P.
dc.contributor.author Guerra Arteaga, Mariella
dc.contributor.author Brayne, C.
dc.contributor.author Prince, M.
dc.date.accessioned 2022-01-18T19:26:49Z
dc.date.available 2022-01-18T19:26:49Z
dc.date.issued 2011
dc.identifier.uri https://hdl.handle.net/20.500.12866/10907
dc.description.abstract Background: There is relative little information about the prevalence and risk factors of co-morbid anxiety and depression in later life. These disorders are often associated with worse response to treatment than either condition alone, and researching their epidemiology in diverse settings is vital to policy makers. We therefore investigated the co-occurrence of anxiety and depressive syndromes amongst older adults living in developing countries and measured the separate and joint effect of these two disorders on levels of associated disability. Method: The 10/66 study carried out cross-cultural surveys of all residents aged 65 years or over (n=15021) in 11 sites in seven countries (People's Republic of China, India, Cuba, Dominican Republic, Venezuela, Mexico and Peru). Anxiety was measured by using the Geriatric Mental State Examination and the Automated Geriatric Examination for Computer Assisted Taxonomy diagnostic system. Depression was assessed according to International Classification of Diseases 10th revision (ICD-10) and EURO-D criteria. Disability was measured by using the World Health Organization's Disablement Assessment Scale Version II. Zero-inflated negative binomial regression models were used to investigate the association of common mental disorders and disability. Results: The prevalence of co-occurring anxiety and depression (with the exclusion of subthreshold disorders) ranged between 0.9% and 4.2% across sites. Gender, socio-economic status, urbanicity and physical co-morbidities were associated with the different co-morbid states. Having both disorders was linked to higher disability scores than having anxiety or depression alone. Conclusions: Given the close association of co-morbid anxiety and depression with disability, new policies to improve prevention, recognition and treatment will be needed to adapt to ageing populations and their mental health needs. en_US
dc.language.iso eng
dc.publisher Crambridge University Press
dc.relation.ispartofseries Psychological Medicine
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Humans en_US
dc.subject article en_US
dc.subject Cross-Sectional Studies en_US
dc.subject cross-sectional study en_US
dc.subject epidemiology en_US
dc.subject Latin America en_US
dc.subject South and Central America en_US
dc.subject comorbidity en_US
dc.subject depression en_US
dc.subject China en_US
dc.subject statistics en_US
dc.subject interview en_US
dc.subject Interviews as Topic en_US
dc.subject urban population en_US
dc.subject Urban Population en_US
dc.subject Sex Distribution en_US
dc.subject sex ratio en_US
dc.subject rural population en_US
dc.subject Rural Population en_US
dc.subject developing country en_US
dc.subject Developing Countries en_US
dc.subject Comorbidity en_US
dc.subject Depressive Disorder en_US
dc.subject Anxiety en_US
dc.subject anxiety disorder en_US
dc.subject India en_US
dc.subject Anxiety Disorders en_US
dc.subject geriatric assessment en_US
dc.subject co-morbidity en_US
dc.subject Geriatric Assessment en_US
dc.subject old age en_US
dc.title Co-occurrence of anxiety and depression amongst older adults in low-and middle-income countries: Findings from the 10/66 study en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1017/S0033291711000444
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.00
dc.relation.issn 1469-8978


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