The hypoxic placenta

Van Patot, M.C.T.; Gassmann, M.; Llanos, A.J.; Ebensperger, G.

dc.contributor.author	Van Patot, M.C.T.
dc.contributor.author	Ebensperger, G.
dc.contributor.author	Gassmann, M.
dc.contributor.author	Llanos, A.J.
dc.date.accessioned	2022-01-18T19:26:50Z
dc.date.available	2022-01-18T19:26:50Z
dc.date.issued	2012
dc.identifier.uri	https://hdl.handle.net/20.500.12866/10940
dc.description.abstract	Hypoxia of the placenta is integral to complications of pregnancy, including preeclampsia, intrauterine growth restriction, and small-for-gestational age babies. Hypoxia in the placenta is associated with vascular remodeling, hypertension, metabolic changes, oxidative stress, mitochondrial dysfunction, and endoplasmic reticular stress. Hypoxia induces similar outcomes in other organs such as the lungs, kidney, and gut. Comparing and contrasting the effects of hypoxia on placental functions and functions of lung, kidney, and gut can lead to novel hypotheses and investigations, furthering our understanding of the impact of hypoxia on these diverse yet similar organs. In this review, we compare and contrast hypoxic placental responses to those in the other organ and cell systems.	en_US
dc.language.iso	eng
dc.publisher	Mary Ann Liebert
dc.relation.ispartofseries	High Altitude Medicine and Biology
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Humans\|Protein Expression	en_US
dc.subject	Altitude	en_US
dc.subject	Blood Pressure	en_US
dc.subject	Pulmonary Hypertension	en_US
dc.subject	Adaptation Physiological	en_US
dc.subject	Anoxia	en_US
dc.subject	Hypoxia	en_US
dc.subject	Oxygen	en_US
dc.subject	Placenta	en_US
dc.subject	Preeclampsia	en_US
dc.subject	Pregnancy	en_US
dc.subject	Oxygen Tension	en_US
dc.subject	Pregnancy Complications	en_US
dc.subject	Conference Paper	en_US
dc.subject	Erythropoietin	en_US
dc.subject	Hypoxia Inducible Factor 2alpha	en_US
dc.subject	Hypoxia Inducible Factor 1alpha	en_US
dc.subject	Altitude Acclimatization	en_US
dc.subject	Oxidative Stress	en_US
dc.subject	Protein Synthesis	en_US
dc.subject	Lung	en_US
dc.subject	Hypertension	en_US
dc.subject	Erythropoietin	en_US
dc.subject	Kidney	en_US
dc.subject	Protein Function	en_US
dc.subject	Fetal Hypoxia	en_US
dc.subject	Gastrointestinal System	en_US
dc.subject	Gastrointestinal Tract	en_US
dc.subject	Kidney	en_US
dc.subject	Maternal Hypertension	en_US
dc.subject	Mitochondria	en_US
dc.subject	Partial Pressure	en_US
dc.subject	Placenta Circulation	en_US
dc.subject	Placenta Disorder	en_US
dc.subject	Placenta Function	en_US
dc.subject	Pulmonary Vascular Remodeling	en_US
dc.subject	Vascular Remodeling	en_US
dc.title	The hypoxic placenta	en_US
dc.type	info:eu-repo/semantics/review
dc.identifier.doi	https://doi.org/10.1089/ham.2012.1046
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn	1557-8682