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dc.contributor.author Van Patot, M.C.T.
dc.contributor.author Ebensperger, G.
dc.contributor.author Gassmann, M.
dc.contributor.author Llanos, A.J.
dc.date.accessioned 2022-01-18T19:26:50Z
dc.date.available 2022-01-18T19:26:50Z
dc.date.issued 2012
dc.identifier.uri https://hdl.handle.net/20.500.12866/10940
dc.description.abstract Hypoxia of the placenta is integral to complications of pregnancy, including preeclampsia, intrauterine growth restriction, and small-for-gestational age babies. Hypoxia in the placenta is associated with vascular remodeling, hypertension, metabolic changes, oxidative stress, mitochondrial dysfunction, and endoplasmic reticular stress. Hypoxia induces similar outcomes in other organs such as the lungs, kidney, and gut. Comparing and contrasting the effects of hypoxia on placental functions and functions of lung, kidney, and gut can lead to novel hypotheses and investigations, furthering our understanding of the impact of hypoxia on these diverse yet similar organs. In this review, we compare and contrast hypoxic placental responses to those in the other organ and cell systems. en_US
dc.language.iso eng
dc.publisher Mary Ann Liebert
dc.relation.ispartofseries High Altitude Medicine and Biology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Humans|Protein Expression en_US
dc.subject Altitude en_US
dc.subject Blood Pressure en_US
dc.subject Pulmonary Hypertension en_US
dc.subject Adaptation Physiological en_US
dc.subject Anoxia en_US
dc.subject Hypoxia en_US
dc.subject Oxygen en_US
dc.subject Placenta en_US
dc.subject Preeclampsia en_US
dc.subject Pregnancy en_US
dc.subject Oxygen Tension en_US
dc.subject Pregnancy Complications en_US
dc.subject Conference Paper en_US
dc.subject Erythropoietin en_US
dc.subject Hypoxia Inducible Factor 2alpha en_US
dc.subject Hypoxia Inducible Factor 1alpha en_US
dc.subject Altitude Acclimatization en_US
dc.subject Oxidative Stress en_US
dc.subject Protein Synthesis en_US
dc.subject Lung en_US
dc.subject Hypertension en_US
dc.subject Erythropoietin en_US
dc.subject Kidney en_US
dc.subject Protein Function en_US
dc.subject Fetal Hypoxia en_US
dc.subject Gastrointestinal System en_US
dc.subject Gastrointestinal Tract en_US
dc.subject Kidney en_US
dc.subject Maternal Hypertension en_US
dc.subject Mitochondria en_US
dc.subject Partial Pressure en_US
dc.subject Placenta Circulation en_US
dc.subject Placenta Disorder en_US
dc.subject Placenta Function en_US
dc.subject Pulmonary Vascular Remodeling en_US
dc.subject Vascular Remodeling en_US
dc.title The hypoxic placenta en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1089/ham.2012.1046
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 1557-8682


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