Universidad Peruana Cayetano Heredia

Photoprotection against the UVB-induced oxidative stress and epidermal damage in mice using leaves of three different varieties of Lepidium meyenii (maca)

Mostrar el registro sencillo del ítem

dc.contributor.author Gonzales-Castañeda, C.
dc.contributor.author Rivera, V.
dc.contributor.author Chirinos, A.L.
dc.contributor.author Evelson, P.
dc.contributor.author Gonzales Rengifo, Gustavo Francisco
dc.date.accessioned 2022-01-18T19:26:52Z
dc.date.available 2022-01-18T19:26:52Z
dc.date.issued 2011
dc.identifier.uri https://hdl.handle.net/20.500.12866/10976
dc.description.abstract Background Skin exposure to ultraviolet (UV) B radiation leads to epidermal damage and generation of reactive oxygen species. The photoprotective effect of extracts of three varieties of leaves (red, yellow, and black) from maca (Lepidium meyenii), a plant from the Peruvian highlands, was assessed in mouse skin exposed to UVB radiation. Materials and methods The hydroalcoholic extracts of three varieties of maca leaves were applied topically to the dorsal skin of young-adult male mice prior to exposition to UVB radiation. Results The three varieties had UVA/UVB absorptive properties and presented antioxidant activity, being highest with red maca, followed by black and yellow maca. The three varieties of maca leaves prevented the development of sunburn cells, epidermal hyperplasia, leukocytic infiltration, and other alterations produced by UVB radiation. Mice treated with black maca showed the highest superoxide dismutase levels, and mice treated with black and yellow maca showed higher catalase levels in skin, whereas red maca protected the skin and liver against significant increases in the lipid peroxidation activity observed in the unprotected animals. Conclusion The presence of significant antioxidant activity and the inhibition of lipid peroxidation suggest that the observed protection could be partly attributable to this mechanism. en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartofseries International Journal of Dermatology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Biopsy en_US
dc.subject animal experiment en_US
dc.subject animal tissue en_US
dc.subject Animals en_US
dc.subject Mice en_US
dc.subject mouse en_US
dc.subject non|epidermis hyperplasia en_US
dc.subject erythema en_US
dc.subject skin biopsy en_US
dc.subject skin en_US
dc.subject epidermis en_US
dc.subject Plant Extracts en_US
dc.subject Lepidium en_US
dc.subject Lepidium meyenii extract en_US
dc.subject medicinal plant en_US
dc.subject Antioxidants en_US
dc.subject plant leaf en_US
dc.subject cell infiltration en_US
dc.subject leukocyte en_US
dc.subject lipid peroxidation en_US
dc.subject Oxidative Stress en_US
dc.subject Liver en_US
dc.subject Lipid Peroxidation en_US
dc.subject ultraviolet B radiation en_US
dc.subject Ultraviolet Rays en_US
dc.subject Lepidium meyenii en_US
dc.subject Plant Leaves en_US
dc.subject Phytotherapy en_US
dc.subject antioxidant activity en_US
dc.subject Catalase en_US
dc.subject cell damage en_US
dc.subject Epidermis en_US
dc.subject radiation protection en_US
dc.subject Sunburn en_US
dc.subject Superoxide Dismutase en_US
dc.title Photoprotection against the UVB-induced oxidative stress and epidermal damage in mice using leaves of three different varieties of Lepidium meyenii (maca) en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1111/j.1365-4632.2010.04793.x
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.15
dc.relation.issn 1365-4632


Ficheros en el ítem

Ficheros Tamaño Formato Ver

No hay ficheros asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

info:eu-repo/semantics/restrictedAccess Excepto si se señala otra cosa, la licencia del ítem se describe como info:eu-repo/semantics/restrictedAccess

Buscar en el Repositorio


Listar

Panel de Control

Estadísticas