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Serum testosterone levels and score of chronic mountain sickness in Peruvian men natives at 4340m

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dc.contributor.author Gonzales Rengifo, Gustavo Francisco
dc.contributor.author Tapia Aguirre, Vilma Lucrecia
dc.contributor.author Gasco Tantachuco, Manuel Enrique
dc.contributor.author Gonzales-Castañeda, C.
dc.date.accessioned 2022-01-18T19:26:52Z
dc.date.available 2022-01-18T19:26:52Z
dc.date.issued 2011
dc.identifier.uri https://hdl.handle.net/20.500.12866/10978
dc.description.abstract Life at high altitudes (>4000m) is associated with higher erythropoiesis. Haemoglobin ≥21gdl-1 is considered as excessive erythrocytosis and is a sign of chronic mountain sickness (CMS). The present study was designed to determine an association between serum testosterone (T) and serum oestradiol (E2) levels with the score of CMS. One hundred and seventeen men natives from low altitude (150m) and 103 men natives from high altitude (4340m) were studied. The presence of breathlessness or palpitations, sleep disturbance, cyanosis, dilatation of veins, paraesthesia, headaches, tinnitus and Hb ≥21gdl-1, have been included for the CMS score. Men living at high altitude had higher CMS score (P<0.001), serum T (P<0.05) and serum E2 levels (P<0.04) and had lower serum luteinising hormone levels (P<0.005) than men living at sea level. At high altitude, the group with the highest CMS score (≥10) showed higher chronological age, SpO2, serum T and ratio T/E2 than the group with CMS score of ≤4. Some symptoms of CMS as sleep disorders and paraesthesia were more related to high serum T level; cyanosis was more related to higher haemoglobin values. In conclusion, higher serum T levels were associated to higher scores of CMS. en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartofseries Andrologia
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Humans en_US
dc.subject Peru en_US
dc.subject Major Clinical Study en_US
dc.subject Headache en_US
dc.subject Altitude en_US
dc.subject Altitude Disease en_US
dc.subject Altitude Sickness en_US
dc.subject Groups By Age en_US
dc.subject Dyspnea en_US
dc.subject Ethnic Group en_US
dc.subject Hemoglobin Blood Level en_US
dc.subject Testosterone en_US
dc.subject Chronic Mountain Sickness en_US
dc.subject Correlation Analysis en_US
dc.subject Cyanosis en_US
dc.subject Estradiol Blood Level en_US
dc.subject Excessive Erythrocytosis en_US
dc.subject Heart Palpitation en_US
dc.subject Luteinizing Hormone Blood Level en_US
dc.subject Men en_US
dc.subject Oxygen Saturation en_US
dc.subject Oxygen Tension en_US
dc.subject Paresthesia en_US
dc.subject Scoring System en_US
dc.subject Sea Level en_US
dc.subject Sex Steroids en_US
dc.subject Sleep Disorder en_US
dc.subject Symptomatology en_US
dc.subject Testosterone Blood Level en_US
dc.subject Tinnitus en_US
dc.subject Vasodilatation en_US
dc.title Serum testosterone levels and score of chronic mountain sickness in Peruvian men natives at 4340m en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1111/j.1439-0272.2010.01046.x
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.01
dc.relation.issn 1439-0272


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