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Addressing geographical variation in the progression of non-communicable diseases in Peru: The CRONICAS cohort study protocol

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dc.contributor.author Miranda, J. Jaime
dc.contributor.author Bernabé Ortiz, Antonio
dc.contributor.author Smeeth, L.
dc.contributor.author Gilman, Robert Hugh
dc.contributor.author Checkley, W.
dc.contributor.author Casas, J.P.
dc.contributor.author Smith, G.D.
dc.contributor.author Ebrahim, S.
dc.contributor.author Gamboa, Raúl
dc.contributor.author García Lescano, Héctor Hugo
dc.contributor.author Huicho Oriundo, Luis
dc.contributor.author Málaga Rodríguez, Germán Javier
dc.contributor.author Montori, V.M.
dc.contributor.author Diette, G.B.
dc.contributor.author León-Velarde, Fabiola
dc.contributor.author Rivera, Maria
dc.contributor.author Wise, R.A.
dc.contributor.author Sacksteder, K.
dc.date.accessioned 2022-01-18T19:26:54Z
dc.date.available 2022-01-18T19:26:54Z
dc.date.issued 2012
dc.identifier.uri https://hdl.handle.net/20.500.12866/11004
dc.description.abstract Background: The rise in non-communicable diseases in developing countries has gained increased attention. Given that around 80% of deaths related to noncommunicable diseases occur in low- and middleincome countries, there is a need for local knowledge to address such problems. Longitudinal studies can provide valuable information about disease burden of non-communicable diseases in Latin America to inform both public health and clinical settings. Methods: The CRONICAS cohort is a longitudinal study performed in three Peruvian settings that differ by degree of urbanisation, level of outdoor and indoor pollution and altitude. sought to enrol an age- and sex-stratified random sample of 1000 participants at each site. Study procedures include questionnaires on socio-demographics and wellknown risk factors for cardiopulmonary disease, blood draw, anthropometry and body composition, blood pressure and spirometry before and after bronchodilators. All participants will be visited at baseline, at 20 and 40 months. A random sample of 100 households at each site will be assessed for 24 h particulate matter concentration. Primary outcomes include prevalence of risk factors for cardiopulmonary diseases, changes in blood pressure and blood glucose over time and decline in lung function. Discussion: There is an urgent need to characterise the prevalence and burden of non-communicable diseases in low- and middle-income countries. Peru is a middle-income country currently undergoing a rapid epidemiological transition. This longitudinal study will provide valuable information on cardiopulmonary outcomes in three different settings and will provide a platform to address potential interventions that are locally relevant or applicable to other similar settings in Latin America. en_US
dc.language.iso eng
dc.publisher BMJ Publishing Group
dc.relation.ispartofseries BMJ Open
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Peru en_US
dc.subject risk factor en_US
dc.subject article en_US
dc.subject cohort analysis en_US
dc.subject major clinical study en_US
dc.subject geographic distribution en_US
dc.subject cardiovascular disease en_US
dc.subject hypertension en_US
dc.subject prevalence en_US
dc.subject demography en_US
dc.subject disease course en_US
dc.subject body composition en_US
dc.subject longitudinal study en_US
dc.subject social status en_US
dc.subject diabetes mellitus en_US
dc.subject glucose blood level en_US
dc.subject spirometry en_US
dc.subject anthropometric parameters en_US
dc.subject blood pressure measurement en_US
dc.subject chronic obstructive lung disease en_US
dc.subject diseases en_US
dc.subject lung function test en_US
dc.subject noncommunicable disease en_US
dc.title Addressing geographical variation in the progression of non-communicable diseases in Peru: The CRONICAS cohort study protocol en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1136/bmjopen-2011-000610
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.00
dc.relation.issn 2044-6055


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