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Biomarkers of fluoride in children exposed to different sources of systemic fluoride

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dc.contributor.author Buzalaf, M.A.R.
dc.contributor.author Rodrigues, M.H.C.
dc.contributor.author Pessan, J.P.
dc.contributor.author Leite, A.L.
dc.contributor.author Arana, A.
dc.contributor.author Villena, R.S.
dc.contributor.author Forte, F.D.S.
dc.contributor.author Sampaio, F.C.
dc.date.accessioned 2022-01-18T19:34:35Z
dc.date.available 2022-01-18T19:34:35Z
dc.date.issued 2011
dc.identifier.uri https://hdl.handle.net/20.500.12866/11022
dc.description.abstract There has been no comparison between fluoride concentrations in urine and nails of children exposed to different sources of systemic fluoride. The aim of this study was to compare the relationship between fluoride intake with urinary fluoride excretion and fluoride concentrations in fingernails and toenails of children receiving fluoride from artificially fluoridated water (0.6-0.8 mg F/L, n = 25), naturally fluoridated water (0.6-0.9 mg F/L, n = 21), fluoridated salt (180-200 mg F/Kg, n = 26), and fluoridated milk (0.25 mg F, n = 25). A control population was included (no systemic fluoride, n = 24). Fluoride intake from diet and dentifrice, urinary fluoride excretion, and fluoride concentrations in fingernails/toenails were evaluated. Fluoride was analyzed with an ion-selective electrode. Urinary fluoride excretion in the control community was significantly lower when compared with that in the fluoridated cities, except for the naturally fluoridated community. However, the same pattern was not as evident for nails. Both urinary fluoride output and fluoride concentrations in fingernails/toenails were significantly correlated to total fluoride intake. However, the correlation coefficients for fluoride intake and urinary fluoride output were lower (r = 0.28, p < 0.01) than those observed for fingernails/toenails (r = 0.36, p < 0.001), suggesting that nails might be slightly better indicators of fluoride intake at the individual level. en_US
dc.language.iso eng
dc.publisher SAGE Publications
dc.relation.ispartofseries Journal of Dental Research
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Case-Control Studies en_US
dc.subject Child en_US
dc.subject Child, Preschool en_US
dc.subject Humans en_US
dc.subject preschool child en_US
dc.subject Animals en_US
dc.subject metabolism en_US
dc.subject Analysis of Variance en_US
dc.subject Biological Markers en_US
dc.subject multicenter study en_US
dc.subject water supply en_US
dc.subject milk en_US
dc.subject clinical trial en_US
dc.subject Statistics, Nonparametric en_US
dc.subject urine en_US
dc.subject chemistry en_US
dc.subject analysis of variance en_US
dc.subject Fluorides en_US
dc.subject nonparametric test en_US
dc.subject Water Supply en_US
dc.subject nail en_US
dc.subject Sodium Chloride, Dietary en_US
dc.subject Milk en_US
dc.subject Dentifrices en_US
dc.subject diet en_US
dc.subject Nails en_US
dc.subject salt intake en_US
dc.subject toothpaste en_US
dc.title Biomarkers of fluoride in children exposed to different sources of systemic fluoride en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1177/0022034510385937
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.14
dc.relation.issn 1544-0591


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