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The short-term effects of diammine silver fluoride on tooth sensitivity: A randomized controlled trial

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dc.contributor.author Castillo, J.L.
dc.contributor.author Rivera, S.
dc.contributor.author Aparicio, T.
dc.contributor.author Lazo, R.
dc.contributor.author Aw, T.-C.
dc.contributor.author Mancl, L.L.
dc.contributor.author Milgrom, P.
dc.date.accessioned 2022-01-18T19:34:35Z
dc.date.available 2022-01-18T19:34:35Z
dc.date.issued 2011
dc.identifier.uri https://hdl.handle.net/20.500.12866/11023
dc.description.abstract Tooth sensitivity is a common clinical problem. This multi-center randomized clinical trial assessed the effectiveness and safety of topical diammine silver fluoride. From two sites (Lima and Cusco, Peru), 126 adults with at least one tooth sensitive to compressed air were randomly assigned to either the experimental treatment or sterile water, and pain was assessed by means of a 100-mm visual analogue scale at 24 hours and 7 days. The diammine silver fluoride reduced pain at 7 days at both sites. At the Lima site, the average change in pain scores between baseline and day 7 for the silver fluoride group was -35.8 (SD = 27.7) mm vs. 0.4 (SD = 16.2) mm for the control group (P < 0.001). In Cusco, the average change in pain scores for the silver fluoride group was -23.4 (SD = 21.0) mm and -5.5 (18.1) mm for the control group (P = 0.002). No tissue ulceration, white changes, or argyria was observed. A small number of participants in the silver fluoride group experienced a mild but transient increase in erythema in the gingiva near the tooth. No changes were observed in the Gingival Index. We concluded that diammine silver fluoride is a clinically effective and safe tooth desensitizer. en_US
dc.language.iso eng
dc.publisher SAGE Publications
dc.relation.ispartofseries Journal of Dental Research
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Humans en_US
dc.subject statistical model en_US
dc.subject controlled study en_US
dc.subject Linear Models en_US
dc.subject Analysis of Variance en_US
dc.subject multicenter study en_US
dc.subject randomized controlled trial en_US
dc.subject controlled clinical trial en_US
dc.subject clinical trial en_US
dc.subject chemistry en_US
dc.subject analysis of variance en_US
dc.subject safety en_US
dc.subject Dentin Sensitivity en_US
dc.subject fluoride en_US
dc.subject fluoride varnish en_US
dc.subject Fluorides, Topical en_US
dc.subject silver diamine fluoride en_US
dc.subject Periodontal Index en_US
dc.subject periodontics en_US
dc.subject Administration, Topical en_US
dc.subject Ammonia en_US
dc.subject Dentin Desensitizing Agents en_US
dc.subject diammine silver fluoride en_US
dc.subject fluorides en_US
dc.subject Pain Measurement en_US
dc.subject Safety en_US
dc.subject Silver Compounds en_US
dc.subject silver derivative en_US
dc.subject silver diammine fluoride en_US
dc.subject silver fluoride en_US
dc.subject tooth sensitivity en_US
dc.subject topical drug administration en_US
dc.subject topical en_US
dc.title The short-term effects of diammine silver fluoride on tooth sensitivity: A randomized controlled trial en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1177/0022034510388516
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.14
dc.relation.issn 1544-0591


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