Universidad Peruana Cayetano Heredia

Why do women reject bisphosphonates for osteoporosis? a videographic study

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dc.contributor.author Scoville, E.A.
dc.contributor.author de Leon Lovaton, P.P.
dc.contributor.author Shah, N.D.
dc.contributor.author Pencille, L.J.
dc.contributor.author Montori, V.M.
dc.date.accessioned 2022-01-18T19:34:38Z
dc.date.available 2022-01-18T19:34:38Z
dc.date.issued 2011
dc.identifier.uri https://hdl.handle.net/20.500.12866/11087
dc.description.abstract Background: Despite access to effective, safe, and affordable treatment for osteoporosis, at-risk women may choose not to start bisphosphonate therapy. Understanding the reasons women give for rejecting a clinician's offer of treatment during consultations and how clinician's react to these reasons may help clinicians develop more effective strategies for fracture prevention and medication adherence. Methods: We conducted a videographic evaluation of encounters in the Osteoporosis Choice randomized trial of a decision aid about bisphosphonates vs. usual primary care. Eligible videos involved consultations with women with an estimated 10-year fragility fracture risk >20% who verbalized at least one reason to not take bisphosphonates. Two reviewers independently reviewed eligible videos and verbatim transcripts, classifying patient views about bisphosphonate use, clinicians reponse to those views, and patient adherence at 6 months post visit. Results: Eighteen video recordings (12 with decision aid) were eligible for analyses. We identified 37 reasons for and against bisphosphonate therapy. Eleven patients rejected treatment, offering 9 (average of 2 per patient) unique reasons against initiating bisphosphonates (most common: side effects 39% and distrust of medications in general 33%). When physicians conceded to patient views the outcome was no bisphosphonate use. Adherence to choices at 6 months was 100%. Conclusions: The expression of patient preferences is sometimes unfavorable to bisphosphonates treatment even among well-informed patients at high risk for osteoporotic fractures. At 6 months, patients who expressed concerns about these medicines behaved consistently with the decision made during the visit. en_US
dc.language.iso eng
dc.publisher Public Library of Science
dc.relation.ispartofseries PLoS ONE
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Female en_US
dc.subject Humans en_US
dc.subject risk assessment en_US
dc.subject controlled study en_US
dc.subject major clinical study en_US
dc.subject psychological aspect en_US
dc.subject randomized controlled trial en_US
dc.subject controlled clinical trial en_US
dc.subject treatment response en_US
dc.subject clinical trial en_US
dc.subject drug safety en_US
dc.subject Patient Compliance en_US
dc.subject patient preference en_US
dc.subject primary medical care en_US
dc.subject decision making en_US
dc.subject Patient Acceptance of Health Care en_US
dc.subject drug use en_US
dc.subject Decision Making en_US
dc.subject patient attitude en_US
dc.subject consultation en_US
dc.subject patient coding en_US
dc.subject treatment refusal en_US
dc.subject videorecording en_US
dc.subject bisphosphonic acid derivative en_US
dc.subject bone density conservation agent en_US
dc.subject Bone Density Conservation Agents en_US
dc.subject Diphosphonates en_US
dc.subject fragility fracture en_US
dc.subject Osteoporosis en_US
dc.title Why do women reject bisphosphonates for osteoporosis? a videographic study en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1371/journal.pone.0018468
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.00
dc.relation.issn 1932-6203


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