We read with interest the article by Champigneulle et al. who observed high COVID-19 seropositivity in La Rinconada (Peru), the highest city in the word (Champigneulle et al. 2021). These results suggest dissemination of COVID-19 even at high altitudes. However, some authors have reported that COVID-19 mortality is lower in high-altitude populations (Quevedo-Ramirez et al., 2020; Thompson et al., 2021). As the evolution of the pandemic progresses, we noticed that there has been an increase in research on the relationship between high altitude and COVID-19 mortality in Peru and ohter countries with people living at high altitude. The objective of this communication was to analyze published studies on this relationship in Peruvian inhabitants...