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Superficial mycosis, at the site or distant to the surgical site, appears to predispose patients to bacterial periprosthetic joint infections.

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dc.contributor.author Lin, Feitai
dc.contributor.author Li, William T.
dc.contributor.author Fuentes-Rivera, Lorena
dc.contributor.author Parvizi, Javad
dc.date.accessioned 2022-02-01T21:18:28Z
dc.date.available 2022-02-01T21:18:28Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/20.500.12866/11311
dc.description.abstract BACKGROUND: It is traditionally believed that presence of fungal infection in the nail or skin of patients is a risk factor for subsequent infection. The literature is devoid of any evidence to confirm or refute this belief. This study examined a possible relationship between the presence of superficial skin or nail mycoses and subsequent periprosthetic joint infection (PJI) in patients undergoing total joint arthroplasty (TJA). METHODS: This is a single-centre, retrospective study of patients who underwent primary TJA between 2000 and 2018. 55 patients with superficial mycoses of skin or nail, at the time of arthroplasty were identified and a variable number matching with up to a 1:5 ratio was performed with 182 patients undergoing TJA who had no superficial mycosis. The groups were further divided into knee and hip TJA. The outcome of TJA in the cohorts was compared. RESULTS: Preoperative demographics were similar between the 2 groups. The incidence of PJI in patients undergoing TKA within a year was significantly higher in patients with superficial mycosis at 8.6% (3/35) compared to 0% (0/120) in patients without mycosis. However, all infections were caused by bacterial species and none were fungal. Multiple regression analysis demonstrated that the presence of superficial mycosis had a strong correlation with development of PJI postoperatively in our TKA cohort. CONCLUSIONS: Identification of fungal infection (mycosis) of skin and nail in patients awaiting TJA is important. These patients appear to have a higher risk for developing bacterial PJI than those without fungal infections. Further study is needed to determine if treatment of these patients prior to arthroplasty stands to reverse the high risk for PJI that these patients carry en_US
dc.language.iso eng
dc.publisher SAGE Publications
dc.relation.ispartofseries Hip International
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject risk factor en_US
dc.subject skin en_US
dc.subject Fungal infection en_US
dc.subject nail en_US
dc.subject periprosthetic joint infection en_US
dc.subject total joint arthroplasty en_US
dc.title Superficial mycosis, at the site or distant to the surgical site, appears to predispose patients to bacterial periprosthetic joint infections. en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1177/11207000211037316
dc.relation.issn 1724-6067


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