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Plasma cytokines during acute human fascioliasis

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dc.contributor.author Aron-Said, Catalina
dc.contributor.author Montes Delgado, Martin
dc.contributor.author White Jr, A. Clinton
dc.contributor.author Cabada, Miguel M.
dc.date.accessioned 2022-02-17T19:23:13Z
dc.date.available 2022-02-17T19:23:13Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/20.500.12866/11392
dc.description.abstract Fascioliasis is a foodborne trematode endemic worldwide. Children under 15 years have the highest prevalence of infection. We hypothesized that acute fascioliasis would be associated with more pronounced cytokine changes than in chronic disease or no helminth infections. To test this hypothesis, 33 children who lived in the Peruvian highlands were classified into 3 groups: acute fascioliasis, chronic fascioliasis, and no helminth infection. Type Th1, Th2, and Th17 cytokines were measured in plasma by cytometric bead array. Children with acute infection had higher levels of IL-5 and IL-17 compared with controls (p < 0.001 and p < 0.007, respectively). The increased IL-5 plasma concentration in children with acute infection was associated with the eosinophilia found in that group. en_US
dc.language.iso eng
dc.publisher Springer Verlag
dc.relation.ispartofseries Parasitology Research
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Fasciola en_US
dc.subject IL-5 en_US
dc.subject IL-17 en_US
dc.title Plasma cytokines during acute human fascioliasis en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1007/s00436-021-07230-8
dc.relation.issn 1432-1955


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