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Associations of Urban Environment Features with Hypertension and Blood Pressure across 230 Latin American Cities

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dc.contributor.author Avila-Palencia, Ione
dc.contributor.author Rodriguez, Daniel A
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Moore, Kari
dc.contributor.author Gouveia, Nelson
dc.contributor.author Moran, Mika R.
dc.contributor.author Caiaffa, Waleska T.
dc.contributor.author Diez Roux, Ana V.
dc.date.accessioned 2022-03-23T16:54:19Z
dc.date.available 2022-03-23T16:54:19Z
dc.date.issued 2022
dc.identifier.uri https://hdl.handle.net/20.500.12866/11464
dc.description.abstract BACKGROUND: Features of the urban physical environment may be linked to the development of high blood pressure, a leading risk factor for global burden of disease. OBJECTIVES: We examined associations of urban physical environment features with hypertension and blood pressure measures in adults across 230 Latin American cities. METHODS: In this cross-sectional study we used health, social, and built environment data from the SALud URBana en América Latina (SALURBAL) project. The individual-level outcomes were hypertension and levels of systolic and diastolic blood pressure. The exposures were city and subcity built environment features, mass transit infrastructure, and green space. Odds ratios (ORs) and mean differences and 95% confidence intervals (CIs) were estimated using multilevel logistic and linear regression models, with single-and multiple-exposure models adjusted for individual-level age, sex, education, and subcity educational attainment. RESULTS: A total of 109,176 participants from 230 cities and eight countries were included in the hypertension analyses and 50,228 participants from 194 cities and seven countries were included in the blood pressure measures analyses. Participants were 18–97 years of age. In multiple-exposure models, higher city fragmentation was associated with higher odds of having hypertension (OR per standard deviation ðSDÞ increase = 1:11; 95% CI: 1.01, 1.21); presence (vs. no presence) of mass transit in the city was associated with higher odds of having hypertension (OR = 1:30; 95% CI: 1.09, 1.54); higher subcity population density was associated with lower odds of having hypertension (OR per SD increase = 0:90; 95% CI: 0.85, 0.94); and higher subcity intersection density was associated with higher odds of having hypertension [OR per SD increase = 1:09; 95% CI: 1.04, 1.15). The presence of mass transit was also associated with slightly higher systolic and diastolic blood pressure in multiple-exposure models adjusted for treatment. Except for the association between intersection density and hypertension, associations were attenuated after adjustment for country. An inverse association of greenness with continuous blood pressure emerged after country adjustment. DISCUSSION: Our results suggest that urban physical environment features—such as fragmentation, mass transit, population density, and intersection density—may be related to hypertension in Latin American cities. Reducing chronic disease risks in the growing urban areas of Latin America may require attention to integrated management of urban design and transport planning. https://doi.org/10.1289/EHP7870. en_US
dc.language.iso eng
dc.publisher National Institute of Environmental Health Sciences
dc.relation.ispartofseries Environmental Health Perspectives
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Urban Environment en_US
dc.subject Hypertension en_US
dc.subject Blood Pressure en_US
dc.subject Latin America en_US
dc.title Associations of Urban Environment Features with Hypertension and Blood Pressure across 230 Latin American Cities en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1289/EHP7870
dc.relation.issn 1552-9924


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