Universidad Peruana Cayetano Heredia

High mortality among hospitalized adult patients with COVID-19 pneumonia in Peru: A single centre retrospective cohort study.

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dc.contributor.author Mas Ubillus, Guiliana
dc.contributor.author Ortiz, Pedro J.
dc.contributor.author Huaringa-Marcelo, Jorge
dc.contributor.author Sarzo-Miranda, Paola
dc.contributor.author Munoz-Aguirre, Patricia
dc.contributor.author Diaz-Ramos, Alejandra
dc.contributor.author Arribasplata-Purizaca, Kattia
dc.contributor.author Mendoza, Doris
dc.contributor.author Rojas-Poma, Juan
dc.contributor.author Marcelo-Ruiz, Cristian
dc.contributor.author Ayala-Diaz, Pedro
dc.contributor.author Hidalgo-Arroyo, Edwin
dc.contributor.author Tupia-Cespedes, Lourdes
dc.date.accessioned 2022-03-23T16:54:20Z
dc.date.available 2022-03-23T16:54:20Z
dc.date.issued 2022
dc.identifier.uri https://hdl.handle.net/20.500.12866/11476
dc.description.abstract Background: Peru is the country with the world’s highest COVID-19 death rate per capita. Characteristics associated with increased mortality among adult patients with COVID-19 pneumonia in this setting are not well described. Methods: Retrospective, single-center cohort study including 1537 adult patients hospitalized with a diagnosis of SARS-CoV-2 pneumonia between May 2020 and August 2020 at a national hospital in Lima, Peru. The primary outcome measure was in-hospital mortality. Results: In-hospital mortality was 49.71%. The mean age was 60 ± 14.25 years, and 68.38% were males. We found an association between mortality and inflammatory markers, mainly leukocytes, D-dimer, lactate dehydrogenase, C-reactive protein and ferritin. A multivariate model adjusted for age, hypertension, diabetes mellitus, and corticosteroid use demonstrated that in-hospital mortality was associated with greater age (RR: 2.01, 95%CI: 1.59–2.52) and a higher level of oxygen requirement (RR: 2.77, 95%CI: 2.13–3.62). Conclusions: In-hospital mortality among COVID-19 patients in Peru is high and is associated with greater age and higher oxygen requirements. en_US
dc.language.iso eng
dc.publisher Public Library of Science
dc.relation.ispartofseries PLoS ONE
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject High mortality en_US
dc.subject hospitalized adult patients en_US
dc.subject COVID-19 pneumonia en_US
dc.subject Peru en_US
dc.subject cohort study en_US
dc.title High mortality among hospitalized adult patients with COVID-19 pneumonia in Peru: A single centre retrospective cohort study. en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1371/journal.pone.0265089
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 1932-6203


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