Non-alcoholic Fatty Liver Disease prevalence in Latin America: A systematic review and meta-analysis.

Barrón, Karina M. Aparicio; Rojas, Yesmi A. Ortega; Cuellar, Claudia L. Vidal; Verdugo, Juan Pablo Arab; Miranda, Adelina Lozano

dc.contributor.author	Rojas, Yesmi A. Ortega
dc.contributor.author	Cuellar, Claudia L. Vidal
dc.contributor.author	Barrón, Karina M. Aparicio
dc.contributor.author	Verdugo, Juan Pablo Arab
dc.contributor.author	Miranda, Adelina Lozano
dc.date.accessioned	2022-06-01T13:53:57Z
dc.date.available	2022-06-01T13:53:57Z
dc.date.issued	2022
dc.identifier.uri	https://hdl.handle.net/20.500.12866/11737
dc.description.abstract	Non-alcoholic fatty liver disease (NAFLD) produces high morbidity and mortality rates. Its worldwide prevalence is 25%, but evidence from Latin America (LA) is lacking. We aimed to estimate the prevalence of NAFLD in the adult population of LA. We conducted a systematic review and meta-analysis. Data were collected from OVID, Cochrane Library and LILACS search engines. We used terms related to NAFLD and LA countries. Observational studies in adults who were born and live in LA were included. Two reviewers evaluated the articles, extracted data and assessed the risk of bias. Discrepancies were resolved by consensus or by a third reviewer. A validated tool was used to assess risk of bias. We found and analyzed 19 articles (n=5625). The prevalence in the general and captive population found was 24%. Populations with type 2 diabetes mellitus or obesity had a higher mean prevalence that reached 68%. We concluded that the average prevalence of NAFLD in LA is around 24%. Among high-risk groups, this value increases to 68%. Further studies in the general population using appropriate designs are required for an accurate estimate of the prevalence of NAFLD in LA.	en_US
dc.language.iso	eng
dc.publisher	Elsevier
dc.relation.ispartofseries	Annals of Hepatology
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Latin America	en_US
dc.subject	systematic review	en_US
dc.subject	NAFLD	en_US
dc.subject	Non-alcoholic fatty liver disease	en_US
dc.title	Non-alcoholic Fatty Liver Disease prevalence in Latin America: A systematic review and meta-analysis.	en_US
dc.type	info:eu-repo/semantics/review
dc.identifier.doi	https://doi.org/10.1016/j.aohep.2022.100706
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.02.19
dc.relation.issn	2659-5982