Universidad Peruana Cayetano Heredia

A Functional Assessment Tool to Distinguish Controls From Alzheimer's Disease in Lima, Peru

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dc.contributor.author Custodio, N
dc.contributor.author Montesinos, R
dc.contributor.author Chambergo-Michilot, D
dc.contributor.author Herrera-Perez, E
dc.contributor.author Pintado-Caipa, M
dc.contributor.author Seminario, GW
dc.contributor.author Cuenca, J
dc.contributor.author Mesia, L
dc.contributor.author Failoc-Rojas, VE
dc.contributor.author Diaz, MM
dc.date.accessioned 2022-06-25T20:36:44Z
dc.date.available 2022-06-25T20:36:44Z
dc.date.issued 2022
dc.identifier.uri https://hdl.handle.net/20.500.12866/11899
dc.description.abstract Background: The Alzheimer’s Disease Cooperative Study-Activities of Daily Living (ADCS-ADL) scale is a versatile functional assessment tool for patients with Alzheimer’s disease (ad). We evaluated its performance in controls, Peruvians with MCI or AD. Methods: A cross-sectional study of older adults attending a neurology institute in Lima (Peru) with mild cognitive impairment (MCI), ad or cognitively healthy. Test-retest reliability (intraclass correlation coefficient, ICC; internal consistency, Cronbach’s alpha) and validity were assessed. Results: We enrolled 276 individuals (ad: 113, MCI: 68, controls: 95) with no age, sex, educational level, and depressive symptom differences. Reliability was ideal (ICC: .996), and Cronbach’s alpha was adequate (.937). The ADCS-ADL could not differentiate MCI from controls but did differentiate ad severity. The ADCS-ADL correlated highly with nearly all tools. Conclusions: The ADCS-ADL scale is reliable in a population with ad in Lima, Peru. Future work may validate a tool for Peruvians with lower educational levels. en_US
dc.language.iso eng
dc.publisher SAGE Publications
dc.relation.ispartofseries American Journal of Alzheimer's Disease and Other Dementias
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject alzheimer disease en_US
dc.subject dementia en_US
dc.subject neurocognitive disorders en_US
dc.subject peru en_US
dc.subject validation study en_US
dc.title A Functional Assessment Tool to Distinguish Controls From Alzheimer's Disease in Lima, Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1177/15333175221104354
dc.relation.issn 1938-2731


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