Universidad Peruana Cayetano Heredia
Lung cancer occurrence after an episode of tuberculosis: a systematic review and meta-analysis.
JavaScript is disabled for your browser. Some features of this site may not work without it.
Mostrar el registro sencillo del ítem
| dc.contributor.author | Cabrera-Sanchez, Javier | |
| dc.contributor.author | Cuba, Vicente | |
| dc.contributor.author | Vega, Victor | |
| dc.contributor.author | Van der Stuyft, Patrick | |
| dc.contributor.author | Otero Vegas, Larissa | |
| dc.date.accessioned | 2022-08-15T20:11:10Z | |
| dc.date.available | 2022-08-15T20:11:10Z | |
| dc.date.issued | 2022 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12866/12048 | |
| dc.description.abstract | INTRODUCTION: People with tuberculosis experience long-term health effects beyond cure, including chronic respiratory diseases. We investigated whether tuberculosis is a risk factor for subsequent lung cancer. METHODS: We searched PubMed, Scopus, Cochrane, Latin American and Caribbean Health Sciences Literature and the Scientific Electronic Library Online for cohort and case-control studies providing effect estimates for the association between tuberculosis and subsequent lung cancer. We pooled estimates through random-effects meta-analysis. The study was registered in PROSPERO (CDR42020178362). RESULTS: Out of 6240 records, we included 29 cohort and 44 case-control studies. Pooled estimates adjusted for age and smoking (assessed quantitatively) were hazard ratio (HR) 1.51 (95% CI 1.30-1.76, I(2)=81%; five studies) and OR 1.74 (95% CI 1.42-2.13, I(2)=59%; 19 studies). The occurrence of lung cancer was increased for 2 years after tuberculosis diagnosis (HR 5.01, 95% CI 3.64-6.89; two studies), but decreased thereafter. Most studies were retrospective, had moderate to high risk of bias, and did not control for passive smoking, environmental exposure and socioeconomic status. Heterogeneity was high. CONCLUSION: We document an association between tuberculosis and lung cancer occurrence, particularly in, but not limited to, the first 2 years after tuberculosis diagnosis. Some cancer cases may have been present at the time of tuberculosis diagnosis and therefore causality cannot be ascertained. Prospective studies controlling for key confounding factors are needed to identify which tuberculosis patients are at the highest risk, as well as cost-effective approaches to mitigate such risk. | en_US |
| dc.language.iso | eng | |
| dc.publisher | European Respiratory Society | |
| dc.relation.ispartofseries | European Respiratory Review | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
| dc.subject | Humans | en_US |
| dc.subject | Retrospective Studies | en_US |
| dc.subject | Prospective Studies | en_US |
| dc.subject | Environmental Exposure | en_US |
| dc.subject | *Tuberculosis | en_US |
| dc.subject | *Lung Neoplasms/diagnosis/epidemiology | en_US |
| dc.title | Lung cancer occurrence after an episode of tuberculosis: a systematic review and meta-analysis. | en_US |
| dc.type | info:eu-repo/semantics/review | |
| dc.identifier.doi | https://doi.org/10.1183/16000617.0025-2022 | |
| dc.relation.issn | 1600-0617 |
Ficheros en el ítem
| Ficheros | Tamaño | Formato | Ver |
|---|---|---|---|
|
No hay ficheros asociados a este ítem. |
|||
Este ítem aparece en la(s) siguiente(s) colección(ones)
-
Artículos en revistas indizadas [4991]
Recuperados de bases de datos bibliográficas
Excepto si se señala otra cosa, la licencia del ítem se describe como info:eu-repo/semantics/restrictedAccess
