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Intrauterine and Extrauterine Environmental PM2.5 Exposure Is Associated with Overweight/Obesity (O/O) in Children Aged 6 to 59 Months from Lima, Peru: A Case-Control Study

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dc.contributor.author Paz-Aparicio, Valeria M.
dc.contributor.author Tapia Aguirre, Vilma Lucrecia
dc.contributor.author Vasquez Apéstegui, Bertha Vanessa
dc.contributor.author Steenland, Kyle
dc.contributor.author Gonzales Rengifo, Gustavo Francisco
dc.date.accessioned 2022-09-09T18:52:23Z
dc.date.available 2022-09-09T18:52:23Z
dc.date.issued 2022
dc.identifier.uri https://hdl.handle.net/20.500.12866/12157
dc.description.abstract There is evidence that PM2.5 could be obesogenic. Lima is one of the most polluted cities in South America, with an increasing prevalence of childhood obesity. This study aimed to determine the association between PM2.5 exposure of children aged 6 to 59 months and being overweight or obese (O/O) in a significant dataset survey. Cases were defined when weight for height Z-score (WHZ) was >2 standard deviations (SD) from the mean, for each sex. A control was defined when WHZ was between ±2 SD. We used a conditional logistic regression model to calculate the odds ratio (OR) between extrauterine and intrauterine PM2.5 exposure and O/O. Extrauterine PM2.5 exposure was evaluated as a 6-month PM2.5 mean prior to the survey. We found a significant association between O/O and extrauterine (OR: 1.57, 1.51–1.63) and intrauterine (OR: 1.99, 1.88–2.12) PM2.5 exposure for an increment of 10 μg/m3. The ORs increased as the quartile increased in both exposures. We observed a higher association in children aged 6–11 months (OR: 3.07, 2.84–3.31). In conclusion, higher levels of PM2.5 in Lima and Callao were associated with cases of O/O in children from 6 to 59 months, with the association higher for prenatal exposure. en_US
dc.language.iso eng
dc.publisher MDPI
dc.relation.ispartofseries Toxics
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject air pollution en_US
dc.subject obesity en_US
dc.subject overweight en_US
dc.subject PM2.5 en_US
dc.subject childhood health en_US
dc.subject intrauterine exposure en_US
dc.subject extrauterine exposure en_US
dc.title Intrauterine and Extrauterine Environmental PM2.5 Exposure Is Associated with Overweight/Obesity (O/O) in Children Aged 6 to 59 Months from Lima, Peru: A Case-Control Study en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.3390/toxics10080487
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.07
dc.relation.issn 2305-6304


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