Universidad Peruana Cayetano Heredia

Association Between the Acquired Immunodeficiency Syndrome and Infection With Salmonella typhi or Salmonella paratyphi in an Endemic Typhoid Area

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dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.contributor.author Frisancho, O.
dc.contributor.author Sanchez, Jorge
dc.contributor.author Liendo, G.
dc.contributor.author Carrillo, Carlos
dc.contributor.author Black, R.E.
dc.contributor.author Morris, J.G.
dc.date.accessioned 2022-10-09T15:38:47Z
dc.date.available 2022-10-09T15:38:47Z
dc.date.issued 1991
dc.identifier.uri https://hdl.handle.net/20.500.12866/12269
dc.description.abstract Eight cases of typhoid and paratyphoid fever were identified during a 4-year period in a cohort of 117 patients who were positive for human immunodeficiency virus in Lima, Peru. Asymptomatic patients with human immundeficiency virus infection and patients with the lymphadenopathy syndrome had a typical clinical presentation and response to therapy. Patients with the acquired immunodeficiency syndrome who were culture positive for Salmonella typhi or Salmonella paratyphi presented with fulminent diarrhea and/or colitis; the two patients for whom at least 2 months of follow-up were available relapsed. In our cohort there were 0.06 cases of typhoid or paratyphoid per patient year of observation; this rate is approximately 60 times that in the general population in Lima, and 25 times that in the 15- to 35-year-old age group. Our data indicate that patients who are positive for human immunodeficiency virus are at significantly increased risk for infection with S typhi and S paratyphi, and suggest that the clinical presentation of these diseases in patients with the acquired immunodeficiency syndrome differs from that seen in immunocompetent hosts. © 1991, American Medical Association. All rights reserved. en_US
dc.language.iso eng
dc.publisher American Medical Association
dc.relation.ispartofseries Archives of Internal Medicine
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Acquired Immunodeficiency Syndrome en_US
dc.subject Human en_US
dc.subject Salmonella paratyphi en_US
dc.subject Salmonella paratyphi B en_US
dc.title Association Between the Acquired Immunodeficiency Syndrome and Infection With Salmonella typhi or Salmonella paratyphi in an Endemic Typhoid Area en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1001/archinte.1991.00400020125026
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08
dc.relation.issn 0003-9926


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