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Efficacy of bone marrow, blood, stool and duodenal contents cultures for bacteriologic confirmation of typhoid fever in children

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dc.contributor.author Vallenas, Constanza
dc.contributor.author Hernández, Herminio
dc.contributor.author Kay, B.
dc.contributor.author Black, R.
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.date.accessioned 2022-10-09T16:39:03Z
dc.date.available 2022-10-09T16:39:03Z
dc.date.issued 1985
dc.identifier.uri https://hdl.handle.net/20.500.12866/12273
dc.description.abstract The relative efficacy of cultures made from duodenal contents (obtained by string capsules), bone marrow, blood and rectal swab was compared in 118 pediatric patients, 2 to 13 years old with suspected typhoid fever. Only 47% of children 2 to 6 years old tolerated the string device, as compared with 89% in children 7 to 13 years old (P < 0.05). The four culture techniques were performed and at least one was positive for Salmonella typhi in 43 patients. Bone marrow cultures were positive in 84% of the confirmed cases, a sensitivity significantly greater than for duodenal contents (42%), blood (44%) and stool (65%) cultures. Higher recovery rates for blood cultures were found during the first week of illness than later (70 vs. 22%). Bone marrow cultures remain the most effective method for the recovery of S. typhi. Stool cultures appear to be more effective in children than in adults. Duodenal contents cultures offer little advantage in young (2 to 6 years old) children. en_US
dc.language.iso eng
dc.publisher Wolters Kluwer Health
dc.relation.ispartofseries Pediatric Infectious Disease Journal
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject blood and hemopoietic system en_US
dc.subject bone marrow en_US
dc.subject child en_US
dc.subject digestive system en_US
dc.subject duodenum content en_US
dc.subject feces en_US
dc.subject human en_US
dc.title Efficacy of bone marrow, blood, stool and duodenal contents cultures for bacteriologic confirmation of typhoid fever in children en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1097/00006454-198509000-00011
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.00
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.03
dc.type.version info:eu-repo/semantics/publishedVersion
dc.relation.issn 1532-0987


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