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Diagnostic value of bone marrow culture in typhoid fever

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dc.contributor.author Guerra-Caceres, Jorge G.
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.contributor.author Crosby-Dagnino, E.
dc.contributor.author Miro-Quesada, M.
dc.contributor.author Carrillo-Parodi, Carlos
dc.date.accessioned 2022-10-09T21:33:53Z
dc.date.available 2022-10-09T21:33:53Z
dc.date.issued 1979
dc.identifier.uri https://hdl.handle.net/20.500.12866/12288
dc.description.abstract The diagnostic efficacy of bone-marrow culture, serial blood cultures and agglutination tests was compared in a prospective study of 60 patients with typhoid fever, two thirds of whom had received prior antibacterial therapy. Salmonella typhi was recovered from marrow cultures in 95% of patients but blood cultures were positive in only 43.3% (P< 0.001). Agglutination tests were eventually diagnostic in 56.7% of patients, but in only 25% at the time of admission. If procedures had been limited to blood cultures and agglutination tests, diagnosis would have been missed in 21.7% of cases. The efficacy of marrow cultures was affected not by the duration of disease but by the extent of antibacterial therapy before presentation. Bacteriological recovery was faster from marrow cultures. en_US
dc.language.iso eng
dc.publisher Oxford University Press
dc.relation.ispartofseries Transactions of the Royal Society of Tropical Medicine and Hygiene
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Diagnostic en_US
dc.subject Typhoid fever en_US
dc.subject Salmonella Typhi en_US
dc.title Diagnostic value of bone marrow culture in typhoid fever en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/0035-9203(79)90020-8
dc.relation.issn 1878-3503


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