Universidad Peruana Cayetano Heredia

Prospective study of the magnitude and duration of changes in tuberculin reactivity during uncomplicated and complicated measles

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dc.contributor.author Tamashiro, Victor G.
dc.contributor.author Perez, Horestes H.
dc.contributor.author Griffin, Diane E.
dc.date.accessioned 2022-10-09T21:43:21Z
dc.date.available 2022-10-09T21:43:21Z
dc.date.issued 1987
dc.identifier.uri https://hdl.handle.net/20.500.12866/12294
dc.description.abstract The suppression of cellular immune responses during measles is thought to contribute to the development of secondary infections which often complicate this disease. To determine whether there was a difference in the altered cellular immune responses of children with and without complications we performed a prospective study of purified protein derivative skin test reactivity in children with natural measles virus infections who had received Bacillus Cal-mette-Guerin as infants. Twenty-five tuberculin-positive children who developed measles (13 uncomplicated and 12 complicated) were skin-tested weekly beginning 1 to 2 weeks before and ending 2 to 7 weeks after the onset of the rash. All children became anergic during the acute phase of measles. Children with complications remained unreactive for a significantly longer period of time after the rash (mean, 4 weeks) than did children without complications (mean, 2.3 weeks, P < 0.001). en_US
dc.language.iso eng
dc.publisher Wolters Kluwer Health
dc.relation.ispartofseries Pediatric Infectious Disease Journal
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Prospective Studies en_US
dc.subject diagnosis en_US
dc.subject human en_US
dc.subject Human en_US
dc.subject clinical article en_US
dc.subject Support, Non-U.S. Gov't en_US
dc.subject priority journal en_US
dc.subject Acute Disease en_US
dc.subject bcg vaccine en_US
dc.subject cellular immunity en_US
dc.subject child en_US
dc.subject Child, Preschool en_US
dc.subject Immune Tolerance en_US
dc.subject Immunity, Cellular en_US
dc.subject measles en_US
dc.subject Measles en_US
dc.subject rash en_US
dc.subject skin test en_US
dc.subject superinfection en_US
dc.subject Support, U.S. Gov't, P.H.S. en_US
dc.subject Tuberculin Test en_US
dc.title Prospective study of the magnitude and duration of changes in tuberculin reactivity during uncomplicated and complicated measles en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1097/00006454-198705000-00007
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08
dc.relation.issn 1532-0987


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