dc.contributor.author |
Dujardin, J.C. |
|
dc.contributor.author |
Bañuls, A.L. |
|
dc.contributor.author |
Dujardin, J.P. |
|
dc.contributor.author |
Arévalo Zelada, Jorge Luis |
|
dc.contributor.author |
Tibayrenc, M. |
|
dc.contributor.author |
Le Ray, D. |
|
dc.date.accessioned |
2022-10-09T22:16:52Z |
|
dc.date.available |
2022-10-09T22:16:52Z |
|
dc.date.issued |
1998 |
|
dc.identifier.uri |
https://hdl.handle.net/20.500.12866/12295 |
|
dc.description.abstract |
Five chromosomes and 17 isoenzyme loci were analysed in 4 allopatric populations of Leishmania (Viannia) peruviana, and molecular distances calculated with 2 estimators, Chromosomal Size Difference Index and Jaccard Distance. Chromosome and isoenzyme data were in overall concordance: 13/30 isolates clustered similarly on the dendrograms constructed from the different estimators, and a significant correlation (P < 0.001)was observed between the molecular distances calculated from the two sets of characters. This indicates an evolutionary association between chromosomal size polymorphism and isoenzymes. Chromosomes have a faster molecular clock than isoenzymes twice as many genotypes were identified by chromosome analysis and significant size differences (for a total of up to 500 kb for 5 chromosomes together) were observed within a given zymodeme. Chromosomes most likely represent better indicators of genetic drift than isoenzymes, as suggested by the higher correlation between both estimators of chromosomal size-polymorphism and eco-geography. Some chromosomes might present an adaptive response to environmental variation. |
en_US |
dc.language.iso |
eng |
|
dc.publisher |
Cambridge University Press |
|
dc.relation.ispartofseries |
Parasitology |
|
dc.rights |
info:eu-repo/semantics/restrictedAccess |
|
dc.rights.uri |
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es |
|
dc.subject |
Drift |
en_US |
dc.subject |
Isoenzymes |
en_US |
dc.subject |
Karyotype |
en_US |
dc.subject |
Leishmania (Viannia) peruviana |
en_US |
dc.subject |
Selection |
en_US |
dc.title |
Comparison of chromosome and isoenzyme polymorphism in geographical populations of Leishmania (Viannia) peruviana |
en_US |
dc.type |
info:eu-repo/semantics/article |
|
dc.identifier.doi |
https://doi.org/10.1017/S0031182098003357 |
|
dc.relation.issn |
1469-8161 |
|