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dc.contributor.author | Dujardin, J.C. | |
dc.contributor.author | Bañuls, A.L. | |
dc.contributor.author | Dujardin, J.P. | |
dc.contributor.author | Arévalo Zelada, Jorge Luis | |
dc.contributor.author | Tibayrenc, M. | |
dc.contributor.author | Le Ray, D. | |
dc.date.accessioned | 2022-10-09T22:16:52Z | |
dc.date.available | 2022-10-09T22:16:52Z | |
dc.date.issued | 1998 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/12295 | |
dc.description.abstract | Five chromosomes and 17 isoenzyme loci were analysed in 4 allopatric populations of Leishmania (Viannia) peruviana, and molecular distances calculated with 2 estimators, Chromosomal Size Difference Index and Jaccard Distance. Chromosome and isoenzyme data were in overall concordance: 13/30 isolates clustered similarly on the dendrograms constructed from the different estimators, and a significant correlation (P < 0.001)was observed between the molecular distances calculated from the two sets of characters. This indicates an evolutionary association between chromosomal size polymorphism and isoenzymes. Chromosomes have a faster molecular clock than isoenzymes twice as many genotypes were identified by chromosome analysis and significant size differences (for a total of up to 500 kb for 5 chromosomes together) were observed within a given zymodeme. Chromosomes most likely represent better indicators of genetic drift than isoenzymes, as suggested by the higher correlation between both estimators of chromosomal size-polymorphism and eco-geography. Some chromosomes might present an adaptive response to environmental variation. | en_US |
dc.language.iso | eng | |
dc.publisher | Cambridge University Press | |
dc.relation.ispartofseries | Parasitology | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | Drift | en_US |
dc.subject | Isoenzymes | en_US |
dc.subject | Karyotype | en_US |
dc.subject | Leishmania (Viannia) peruviana | en_US |
dc.subject | Selection | en_US |
dc.title | Comparison of chromosome and isoenzyme polymorphism in geographical populations of Leishmania (Viannia) peruviana | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1017/S0031182098003357 | |
dc.relation.issn | 1469-8161 |
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