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Diagnosis of typhoid fever using a string capsule device

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dc.contributor.author Benavente, Luis
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.contributor.author Guerra, Jorge G.
dc.contributor.author Grados, Oscar
dc.contributor.author Guerra, Humberto
dc.contributor.author Bravo, Nora
dc.date.accessioned 2022-10-09T23:25:32Z
dc.date.available 2022-10-09T23:25:32Z
dc.date.issued 1984
dc.identifier.uri https://hdl.handle.net/20.500.12866/12313
dc.description.abstract Cultures were made from blood, bone marrow, stool and duodenal contents (obtained with string capsules) from 36 patients with bacteriologically proven typhoid fever on admission to hospital. Duodenal content cultures proved to be as sensitive in diagnosis (86%) as bone marrow (75%) and more effective than blood (42%) and stool (26%) cultures in recovery of Salmonella typhi The sensitivity of duodenal content cultures was not modified by the duration of illness at admission or by previous antibacterial therapy. Even on the seventh day of effective treatment with chloramphenicol, the culture of duodenal contents remained positive in 8 of 17 patients, whereas salmonellae were isolated from stool cultures in only 2 of the same patients. The results obtained with the string capsule, together with the simplicity, economy and acceptability of the procedure, the fact that it can be performed with minimal facilities and the advantages of bacteriological recovery for antibiotic sensitivity testing, suggest that its adoption would be very helpful in efforts to control this disease. en_US
dc.language.iso eng
dc.publisher Oxford University Press
dc.relation.ispartofseries Transactions of the Royal Society of Tropical Medicine and Hygiene
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject antibiotics en_US
dc.subject chloramphenicol en_US
dc.subject enteric fever en_US
dc.subject feces en_US
dc.subject salmonella typhi en_US
dc.subject bone marrow en_US
dc.subject diagnosis en_US
dc.subject duodenum en_US
dc.subject economics en_US
dc.subject anti-bacterial agents en_US
dc.subject medical devices en_US
dc.subject stool culture en_US
dc.subject hospital admission en_US
dc.subject illness length en_US
dc.subject treatment effectiveness en_US
dc.title Diagnosis of typhoid fever using a string capsule device en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/0035-9203(84)90134-2
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn 1878-3503

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