Universidad Peruana Cayetano Heredia

Karyotype Plasticity in Neotropical Leishmanicr. An Index for Measuring Genomic Distance Among L. (V.) Peruviana and L. (V.) Braziliensis Populations

Mostrar el registro sencillo del ítem

dc.contributor.author Dujardin, Jean Claude
dc.contributor.author Timperman, Georges T.
dc.contributor.author De Doncker, Simonne D.
dc.contributor.author Jacquet, Diane
dc.contributor.author Le Ray, Dominique L.
dc.date.accessioned 2022-10-10T00:48:55Z
dc.date.available 2022-10-10T00:48:55Z
dc.date.issued 1995
dc.identifier.uri https://hdl.handle.net/20.500.12866/12332
dc.description.abstract A method for phenetic analysis of karyotype data has been developed for Leishmania populations. Measurement of size difference between chromosomes recognized by a given DNA probe in different isolates led to the formulation of a Chromosome Size Difference Index (CSDI). The method was applied to phenetic analysis of 4 sets of chromosomes – each set being recognized by a different probe – in 37 L. (Viannia) peruviana isolates sampled along a North–South transect through the Peruvian Andes and, in 11 L. (V.) braziliensis isolates from the Amazonian forest (Peru, Bolivia and Brazil). Karyotype variability was better accounted for by CSDI than by a method based on disjunctive encoding of karyotype data. CSDI evidenced the nature of relationships between L. braziliensis and L. peruviana and it provided a coherent picture of geographical and genomic differentiation among parasite populations. The latter did cluster according to their geographical origin. L. braziliensis was found karyotypically more homogeneous than L. peruviana. Within L. peruviana, Northern populations were closer to L. braziliensis than to Southern L. peruviana populations. The validity of karyotypic populations, or karyodemes, was sustained. en_US
dc.language.iso eng
dc.publisher Cambridge University Press
dc.relation.ispartofseries Parasitology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject molecular karyotype en_US
dc.subject phenetic analysis en_US
dc.subject Leishmania peruviana en_US
dc.subject Leishmania braziliensis en_US
dc.subject biogeography en_US
dc.subject polymorphism en_US
dc.title Karyotype Plasticity in Neotropical Leishmanicr. An Index for Measuring Genomic Distance Among L. (V.) Peruviana and L. (V.) Braziliensis Populations en_US
dc.title.alternative Plasticidad cariotipo en Neotropical Leishmanicr. Un índice para medir la distancia genómica entre L. (V.) Peruviana y L. (V.) Poblaciones de Brasiliensis es_PE
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1017/S0031182000081002
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.07
dc.relation.issn 1469-8161


Ficheros en el ítem

Ficheros Tamaño Formato Ver

No hay ficheros asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

info:eu-repo/semantics/restrictedAccess Excepto si se señala otra cosa, la licencia del ítem se describe como info:eu-repo/semantics/restrictedAccess

Buscar en el Repositorio


Listar

Panel de Control

Estadísticas