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dc.contributor.author | León-Velarde, Fabiola | |
dc.contributor.author | Huicho Oriundo, Luis | |
dc.contributor.author | Monge-C,Carlos | |
dc.date.accessioned | 2022-10-10T03:26:44Z | |
dc.date.available | 2022-10-10T03:26:44Z | |
dc.date.issued | 1992 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/12356 | |
dc.description.abstract | The administration of cocaine hydrochloride intraperitoneally (25 mg/kg) produces a drop in VO2 in both normoxic and hypoxic mice. The critical PO2 is also decreased and so is the body temperature. The mitochondrial respiration shows a large fall in ST3 and RCR. The addition of cocaine in-vitro to the incubating medium induces changes in the mitochondrial respiration similar to those found after in-vivo administration. This report shows that in addition to its in-vivo actions cocaine alters the respiratory function of the isolated liver mitochondria. | en_US |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.relation.ispartofseries | Life Sciences | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | Cocaine | en_US |
dc.subject | Mitochondrial respiration | en_US |
dc.subject | Normoxic and hypoxic mice | en_US |
dc.title | Effects of cocaine on oxygen consumption and mitochondrial respiration in normoxic and hypoxic mice | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1016/0024-3205(92)90274-S | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#1.06.01 | |
dc.relation.issn | 0024-3205 |
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