Biomarkers for dementia in Latin American countries: Gaps and opportunities

Diaz, Monica M.; Sellek, Allis F.; Unaucho-Pilalumbo, Martha; Matallana, Diana L.; Arias-Suarez, Bianca P.; Castro-Suarez, Sheila; Barra, Bernardo; Dansilio, Sergio; O'Neill, Santiago; Damian, Andres; Lira, David; Victoria, Cabello G.; Farias, Gonzalo A.; Magrath Guimet, Nahuel; Ibanez, Agustin; Tijms, Betty M.; Gomez, Rodrigo; Cochran, J. Nicholas; Kmaid, Ana; Isabel Behrens, Maria; De la Cruz-Puebla, Myriam; Allegri, Ricardo; Busatto, Geraldo; Duque, Lissette; Franca Resende, Elisa de Paula; Angela Rojas, Luz; Pintado-Caipa, Maritza; Yokoyama, Jennifer S.; Zetterberg, Henrik; Acosta, Daisy; Schilling, Lucas; Contreras, Valeria; Mar Meza, Beatriz; Pina-Escudero, Stefanie D.; Parra, Mario A.; Leon, Tomas; Sabaj, Valentina; Sosa, Ana; Custodio, Nilton; Teixeira, Antonio L.; Takada, Leonel T.; Avalos, Constanza; Nunez, Alberto; Risacher, Shannon; Caramelli, Paulo; Brucki, Sonia M. D.; Slachevsky, Andrea; Ochoa, John; Lopera, Francisco; Orellana, Paulina; de Souza, Leonardo Cruz; Duran-Aniotz, Claudia; Ferreira, Sergio T.; Henriquez, Fernando; Miotto, Eliane C.; Nitrini, Ricardo

dc.contributor.author	Parra, Mario A.
dc.contributor.author	Orellana, Paulina
dc.contributor.author	Leon, Tomas
dc.contributor.author	Victoria, Cabello G.
dc.contributor.author	Henriquez, Fernando
dc.contributor.author	Gomez, Rodrigo
dc.contributor.author	Avalos, Constanza
dc.contributor.author	Damian, Andres
dc.contributor.author	Slachevsky, Andrea
dc.contributor.author	Ibanez, Agustin
dc.contributor.author	Zetterberg, Henrik
dc.contributor.author	Tijms, Betty M.
dc.contributor.author	Yokoyama, Jennifer S.
dc.contributor.author	Pina-Escudero, Stefanie D.
dc.contributor.author	Cochran, J. Nicholas
dc.contributor.author	Matallana, Diana L.
dc.contributor.author	Acosta, Daisy
dc.contributor.author	Allegri, Ricardo
dc.contributor.author	Arias-Suarez, Bianca P.
dc.contributor.author	Barra, Bernardo
dc.contributor.author	Isabel Behrens, Maria
dc.contributor.author	Brucki, Sonia M. D.
dc.contributor.author	Busatto, Geraldo
dc.contributor.author	Caramelli, Paulo
dc.contributor.author	Castro-Suarez, Sheila
dc.contributor.author	Contreras, Valeria
dc.contributor.author	Custodio, Nilton
dc.contributor.author	Dansilio, Sergio
dc.contributor.author	De la Cruz-Puebla, Myriam
dc.contributor.author	de Souza, Leonardo Cruz
dc.contributor.author	Diaz, Monica M.
dc.contributor.author	Duque, Lissette
dc.contributor.author	Farias, Gonzalo A.
dc.contributor.author	Ferreira, Sergio T.
dc.contributor.author	Magrath Guimet, Nahuel
dc.contributor.author	Kmaid, Ana
dc.contributor.author	Lira, David
dc.contributor.author	Lopera, Francisco
dc.contributor.author	Mar Meza, Beatriz
dc.contributor.author	Miotto, Eliane C.
dc.contributor.author	Nitrini, Ricardo
dc.contributor.author	Nunez, Alberto
dc.contributor.author	O'Neill, Santiago
dc.contributor.author	Ochoa, John
dc.contributor.author	Pintado-Caipa, Maritza
dc.contributor.author	Franca Resende, Elisa de Paula
dc.contributor.author	Risacher, Shannon
dc.contributor.author	Angela Rojas, Luz
dc.contributor.author	Sabaj, Valentina
dc.contributor.author	Schilling, Lucas
dc.contributor.author	Sellek, Allis F.
dc.contributor.author	Sosa, Ana
dc.contributor.author	Takada, Leonel T.
dc.contributor.author	Teixeira, Antonio L.
dc.contributor.author	Unaucho-Pilalumbo, Martha
dc.contributor.author	Duran-Aniotz, Claudia
dc.date.accessioned	2022-10-12T18:25:57Z
dc.date.available	2022-10-12T18:25:57Z
dc.date.issued	2022
dc.identifier.uri	https://hdl.handle.net/20.500.12866/12368
dc.description.abstract	Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC) countries remains a serious barrier. Here, we reported a survey to explore the ongoing work, needs, interests, potential barriers, and opportunities for future studies related to biomarkers. The results show that neuroimaging is the most used biomarker (73%), followed by genetic studies (40%), peripheral fluids biomarkers (31%), and cerebrospinal fluid biomarkers (29%). Regarding barriers in LAC, lack of funding appears to undermine the implementation of biomarkers in clinical or research settings, followed by insufficient infrastructure and training. The survey revealed that despite the above barriers, the region holds a great potential to advance dementia biomarkers research. Considering the unique contributions that LAC could make to this growing field, we highlight the urgent need to expand biomarker research. These insights allowed us to propose an action plan that addresses the recommendations for a biomarker framework recently proposed by regional experts.	en_US
dc.language.iso	eng
dc.publisher	Wiley
dc.relation.ispartofseries	Alzheimer's and Dementia
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Biomarkers	en_US
dc.subject	dementia	en_US
dc.subject	Latin America	en_US
dc.title	Biomarkers for dementia in Latin American countries: Gaps and opportunities	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1002/alz.12757
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.01.04
dc.relation.issn	1552-5279