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Seroprevalence and risk factors for human T-cell lymphotropic virus (HTLV-I) infection among ethnically and geographically diverse Peruvian women

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dc.contributor.author Sanchez-Palacios, C.
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.contributor.author Vandamme, A.-M.
dc.contributor.author Maldonado, Y.
dc.date.accessioned 2022-10-25T19:54:11Z
dc.date.available 2022-10-25T19:54:11Z
dc.date.issued 2003
dc.identifier.uri https://hdl.handle.net/20.500.12866/12478
dc.description.abstract Objective: To assess the seroprevalence and risk factors for HTLV-I infection in Peruvian women. Methods: Five hundred and sixty-eight healthy women >20 years of age from three Peruvian regions were randomly selected and screened for HTLV-I. ELISA-reactive sera were confirmed via immunofluorescence assay, recombinant immunoblot assay, Western blot, and PCR. Women from Huanta (n = 303), an Andean city inhabited by indigenous Quechuans, El Carmen (n = 132), a primarily African-American coastal town, and Lima (n = 133), with its Mestizo population, were selected. Results: HTLV-I antibodies were present in 2.5 % (14/568) of women (1.3 % in Huanta, 3.8 % in El Carmen, and 3.8% in Lima); 2.5%, 2.7% and 2.6% of Quechuans, Mestizas and African-Americans, respectively, were infected. History of a blood transfusion (P<0.00002), chronic scabies (P<0.02), having a relative with leukemia (P<0.04), age ±38 years (P<0.03), young age at first intercourse (P<0.04), lifetime partners >4 (P<0.04) educational status (P<0.02) and >4 pregnancies (P<0.03) were significantly associated with infection. Conclusions: HTLV-I is endemic among asymptomatic Peruvian women. Parenteral, vertical and heterosexual transmission are associated with infection. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries International Journal of Infectious Diseases
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Seroprevalence en_US
dc.subject risk factors en_US
dc.subject human T-cell lymphotropic virus (HTLV-I) en_US
dc.subject infection en_US
dc.subject woman en_US
dc.title Seroprevalence and risk factors for human T-cell lymphotropic virus (HTLV-I) infection among ethnically and geographically diverse Peruvian women en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/S1201-9712(03)90009-9
dc.relation.issn 1878-3511


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