Universidad Peruana Cayetano Heredia
Seroprevalence and risk factors for human T-cell lymphotropic virus (HTLV-I) infection among ethnically and geographically diverse Peruvian women
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| dc.contributor.author | Sanchez-Palacios, C. | |
| dc.contributor.author | Gotuzzo Herencia, José Eduardo | |
| dc.contributor.author | Vandamme, A.-M. | |
| dc.contributor.author | Maldonado, Y. | |
| dc.date.accessioned | 2022-10-25T19:54:11Z | |
| dc.date.available | 2022-10-25T19:54:11Z | |
| dc.date.issued | 2003 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12866/12478 | |
| dc.description.abstract | Objective: To assess the seroprevalence and risk factors for HTLV-I infection in Peruvian women. Methods: Five hundred and sixty-eight healthy women >20 years of age from three Peruvian regions were randomly selected and screened for HTLV-I. ELISA-reactive sera were confirmed via immunofluorescence assay, recombinant immunoblot assay, Western blot, and PCR. Women from Huanta (n = 303), an Andean city inhabited by indigenous Quechuans, El Carmen (n = 132), a primarily African-American coastal town, and Lima (n = 133), with its Mestizo population, were selected. Results: HTLV-I antibodies were present in 2.5 % (14/568) of women (1.3 % in Huanta, 3.8 % in El Carmen, and 3.8% in Lima); 2.5%, 2.7% and 2.6% of Quechuans, Mestizas and African-Americans, respectively, were infected. History of a blood transfusion (P<0.00002), chronic scabies (P<0.02), having a relative with leukemia (P<0.04), age ±38 years (P<0.03), young age at first intercourse (P<0.04), lifetime partners >4 (P<0.04) educational status (P<0.02) and >4 pregnancies (P<0.03) were significantly associated with infection. Conclusions: HTLV-I is endemic among asymptomatic Peruvian women. Parenteral, vertical and heterosexual transmission are associated with infection. | en_US |
| dc.language.iso | eng | |
| dc.publisher | Elsevier | |
| dc.relation.ispartofseries | International Journal of Infectious Diseases | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
| dc.subject | Seroprevalence | en_US |
| dc.subject | risk factors | en_US |
| dc.subject | human T-cell lymphotropic virus (HTLV-I) | en_US |
| dc.subject | infection | en_US |
| dc.subject | woman | en_US |
| dc.title | Seroprevalence and risk factors for human T-cell lymphotropic virus (HTLV-I) infection among ethnically and geographically diverse Peruvian women | en_US |
| dc.type | info:eu-repo/semantics/article | |
| dc.identifier.doi | https://doi.org/10.1016/S1201-9712(03)90009-9 | |
| dc.relation.issn | 1878-3511 |
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