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Malaria Resilience in South America: Epidemiology, Vector Biology, and Immunology Insights from the Amazonian International Center of Excellence in Malaria Research Network in Peru and Brazil

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dc.contributor.author Torres Fajardo, Katherine Jessica
dc.contributor.author Ferreira, Marcelo U.
dc.contributor.author Castro, Marcia C.
dc.contributor.author Escalante, Ananias A.
dc.contributor.author Conn, Jan E.
dc.contributor.author Villasis Mayuri, Elizabeth Melisa
dc.contributor.author da Silva Araujo, Maisa
dc.contributor.author Almeida, Gregorio
dc.contributor.author Rodrigues, Priscila T.
dc.contributor.author Corder, Rodrigo M.
dc.contributor.author Fernandes, Anderson R. J.
dc.contributor.author Calil, Priscila R.
dc.contributor.author Ladeia, Winni A.
dc.contributor.author Garcia-Castillo, Stefano S.
dc.contributor.author Gomez, Joaquin
dc.contributor.author do Valle Antonelli, Lis Ribeiro
dc.contributor.author Gazzinelli, Ricardo T.
dc.contributor.author Golenbock, Douglas T.
dc.contributor.author Llanos Cuentas, Elmer Alejandro
dc.contributor.author Gamboa Vilela, Dionicia Baziliza
dc.contributor.author Vinetz, Joseph Michael
dc.date.accessioned 2022-11-15T23:04:37Z
dc.date.available 2022-11-15T23:04:37Z
dc.date.issued 2022
dc.identifier.uri https://hdl.handle.net/20.500.12866/12532
dc.description.abstract The 1990s saw the rapid reemergence of malaria in Amazonia, where it remains an important public health priority in South America. The Amazonian International Center of Excellence in Malaria Research (ICEMR) was designed to take a multidisciplinary approach toward identifying novel malaria control and elimination strategies. Based on geographically and epidemiologically distinct sites in the Northeastern Peruvian and Western Brazilian Amazon regions, synergistic projects integrate malaria epidemiology, vector biology, and immunology. The Amazonian ICEMR's overarching goal is to understand how human behavior and other sociodemographic features of human reservoirs of transmission-predominantly asymptomatically parasitemic people-interact with the major Amazonian malaria vector, Nyssorhynchus (formerly Anopheles) darlingi, and with human immune responses to maintain malaria resilience and continued endemicity in a hypoendemic setting. Here, we will review Amazonian ICEMR's achievements on the synergies among malaria epidemiology, Plasmodium-vector interactions, and immune response, and how those provide a roadmap for further research, and, most importantly, point toward how to achieve malaria control and elimination in the Americas. en_US
dc.language.iso eng
dc.publisher American Journal of Tropical Medicine and Hygiene
dc.relation.ispartofseries American Journal of Tropical Medicine and Hygiene
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Malaria en_US
dc.subject South America en_US
dc.subject Epidemiology en_US
dc.subject Vector Biology en_US
dc.subject Immunology en_US
dc.subject Peru en_US
dc.subject Brazil en_US
dc.title Malaria Resilience in South America: Epidemiology, Vector Biology, and Immunology Insights from the Amazonian International Center of Excellence in Malaria Research Network in Peru and Brazil en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.4269/ajtmh.22-0127
dc.relation.issn 1476-1645


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