Universidad Peruana Cayetano Heredia

Evidence-Based Malaria Control and Elimination in the Amazon: Input from the International Center of Excellence in Malaria Research Network in Peru and Brazil.

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dc.contributor.author Ferreira, Marcelo U.
dc.contributor.author Gamboa Vilela, Dionicia Baziliza
dc.contributor.author Torres Fajardo, Katherine Jessica
dc.contributor.author Rodriguez-Ferrucci, Hugo
dc.contributor.author Soto-Calle, Veronica E.
dc.contributor.author Pardo, Karim
dc.contributor.author Fontoura, Pablo S.
dc.contributor.author Tomko, Sheena S.
dc.contributor.author Gazzinelli, Ricardo T.
dc.contributor.author Conn, Jan E.
dc.contributor.author Castro, Marcia C.
dc.contributor.author Llanos Cuentas, Elmer Alejandro
dc.contributor.author Vinetz, Joseph Michael
dc.date.accessioned 2022-11-15T23:04:37Z
dc.date.available 2022-11-15T23:04:37Z
dc.date.issued 2022
dc.identifier.uri https://hdl.handle.net/20.500.12866/12533
dc.description.abstract Malaria remains endemic in 17 countries in the Americas, where 723,000 cases were reported in 2019. The majority (> 90%) of the regional malaria burden is found within the Amazon Basin, which includes nine countries and territories in South America. Locally generated evidence is critical to provide information to public health decision makers upon which the design of efficient and regionally directed malaria control and elimination programs can be built. Plasmodium vivax is the predominant malaria parasite in the Amazon Basin. This parasite species appears to be more resilient to malaria control strategies worldwide. Asymptomatic Plasmodium infections constitute a potentially infectious reservoir that is typically missed by routine microscopy-based surveillance and often remains untreated. The primary Amazonian malaria vector, Nyssorhynchus (formerly Anopheles) darlingi, has changed its behavior to feed and rest predominantly outdoors, reducing the efficiency of core vector control measures such as indoor residual spraying and distribution of long-lasting insecticide-treated bed nets. We review public health implications of recent field-based research carried out by the Amazonia International Center of Excellence in Malaria Research in Peru and Brazil. We discuss the relative role of traditional and novel tools and strategies for better malaria control and elimination across the Amazon, including improved diagnostic methods, new anti-relapse medicines, and biological larvicides, and emphasize the need to integrate research and public health policymaking. en_US
dc.language.iso eng
dc.publisher American Journal of Tropical Medicine and Hygiene
dc.relation.ispartofseries American Journal of Tropical Medicine and Hygiene
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Malaria en_US
dc.subject Amazon en_US
dc.subject Peru en_US
dc.subject Brazil en_US
dc.title Evidence-Based Malaria Control and Elimination in the Amazon: Input from the International Center of Excellence in Malaria Research Network in Peru and Brazil. en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.4269/ajtmh.21-1272
dc.relation.issn 1476-1645


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