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Cordiosides A and B, two new 19-hydroxy-29-norlanostane glycosides isolated from the flowers of Cordia lutea

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dc.contributor.author Castro Dionicio, Ines Y.
dc.contributor.author Fabre, N.
dc.contributor.author Saffon-Merceron, N.
dc.contributor.author Sauvain, Michel Henri Auguste
dc.contributor.author Castillo Pareja, Denis Helan
dc.contributor.author Jullian, Valérie
dc.date.accessioned 2022-11-15T23:04:38Z
dc.date.available 2022-11-15T23:04:38Z
dc.date.issued 2022
dc.identifier.uri https://hdl.handle.net/20.500.12866/12552
dc.description.abstract We present here the isolation and structural characterization of two undescribed mono-glycosylated triterpenes with a 19-hydroxy-29-norlanostane core. These compounds (1-2) were isolated from an ethanolic extract of the dried flowers of Cordia lutea, a widely used Peruvian traditional medicine. Their structures were determined by examination of their NMR and MS data. For compound 1, its structure was confirmed by single crystal X-ray structural analyses. 1 showed moderate activity against Helicobacter pylori (MIC = 15.6 µg/mL), and was not active against Escherichia coli, Pseudomonas aeruginosa or Staphylococcus aureus (MIC > 125 µg/mL). en_US
dc.description.sponsorship Este trabajo fue financiado parcialmente por CONCYTEC. También se benefició de la financiación del LMI LAVI (Laboratorio conjunto internacional, IRD-UPCH) por parte del IRD. es_PE
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Phytochemistry Letters
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Cordia lutea en_US
dc.subject Boraginaceae en_US
dc.subject Helicobacter pylori en_US
dc.subject Antibacterial en_US
dc.subject 19-Hydroxy-29-norlanostane en_US
dc.subject Peruvian traditional medicine en_US
dc.title Cordiosides A and B, two new 19-hydroxy-29-norlanostane glycosides isolated from the flowers of Cordia lutea en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.phytol.2022.08.015
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.00
dc.relation.issn 1874-3900


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