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dc.contributor.author | Castro Dionicio, Ines Y. | |
dc.contributor.author | Fabre, N. | |
dc.contributor.author | Saffon-Merceron, N. | |
dc.contributor.author | Sauvain, Michel Henri Auguste | |
dc.contributor.author | Castillo Pareja, Denis Helan | |
dc.contributor.author | Jullian, Valérie | |
dc.date.accessioned | 2022-11-15T23:04:38Z | |
dc.date.available | 2022-11-15T23:04:38Z | |
dc.date.issued | 2022 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/12552 | |
dc.description.abstract | We present here the isolation and structural characterization of two undescribed mono-glycosylated triterpenes with a 19-hydroxy-29-norlanostane core. These compounds (1-2) were isolated from an ethanolic extract of the dried flowers of Cordia lutea, a widely used Peruvian traditional medicine. Their structures were determined by examination of their NMR and MS data. For compound 1, its structure was confirmed by single crystal X-ray structural analyses. 1 showed moderate activity against Helicobacter pylori (MIC = 15.6 µg/mL), and was not active against Escherichia coli, Pseudomonas aeruginosa or Staphylococcus aureus (MIC > 125 µg/mL). | en_US |
dc.description.sponsorship | Este trabajo fue financiado parcialmente por CONCYTEC. También se benefició de la financiación del LMI LAVI (Laboratorio conjunto internacional, IRD-UPCH) por parte del IRD. | es_PE |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.relation.ispartofseries | Phytochemistry Letters | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | Cordia lutea | en_US |
dc.subject | Boraginaceae | en_US |
dc.subject | Helicobacter pylori | en_US |
dc.subject | Antibacterial | en_US |
dc.subject | 19-Hydroxy-29-norlanostane | en_US |
dc.subject | Peruvian traditional medicine | en_US |
dc.title | Cordiosides A and B, two new 19-hydroxy-29-norlanostane glycosides isolated from the flowers of Cordia lutea | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1016/j.phytol.2022.08.015 | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.01.00 | |
dc.relation.issn | 1874-3900 |
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